epilepsiaEpilepsy and paroxysmal conditionsЭпилепсия и пароксизмальные состояния2077-83332311-4088IRBIS LLC10.17749/2077-8333/epi.par.con.2025.253epilepsia-1254Research ArticleORIGINAL ARTICLESОРИГИНАЛЬНЫЕ СТАТЬИA relation between stereoelectroencephalography parameters and focal drug-resistant epilepsy surgery outcomesВзаимосвязь параметров стереоэлектроэнцефалографии и исходов хирургического лечения фокальной фармакорезистентной эпилепсииhttps://orcid.org/0000-0003-0506-003XБиякаеваМ. А.BiyakaevaM. A.

Биякаева Мадина Анварбековна

ул. Нижняя Первомайская, д. 70, Москва 105203

Madina A. Biyakaeva

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

https://orcid.org/0000-0003-1800-1055ГордееваЕ. А.GordeyevaE. A.

Гордеева Елизавета Александровна

WoS ResearcherID: S-5582-2018

Scopus ID: 57217866313

ул. Нижняя Первомайская, д. 70, Москва 105203

Elizaveta A. Gordeyeva

WoS ResearcherID: S-5582-2018

Scopus ID: 57217866313

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

gordeevaea@pirogov-center.ruhttps://orcid.org/0009-0004-6077-0063ЛукашеваА. Д.LukashevaA. D.

Лукашева Александра Дмитриевна 

ул. Нижняя Первомайская, д. 70, Москва 105203

Aleksandra D. Lukasheva

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

https://orcid.org/0000-0002-0770-2983УтяшевН. П.UtyashevN. P.

Утяшев Никита Павлович

WoS ResearcherID: IST-9700-2023

Scopus Author ID: 57786938400

ул. Нижняя Первомайская, д. 70, Москва 105203

Nikita P. Utyashev

WoS ResearcherID: IST-9700-2023

Scopus Author ID: 57786938400

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

https://orcid.org/0000-0002-6892-3050УтяшеваА. А.UtyashevaA. A.

Утяшева Анна Алексеевна

ул. Нижняя Первомайская, д. 70, Москва 105203

Anna A. Utyasheva

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

https://orcid.org/0000-0002-2713-5904ПедяшН. В.PedyashN. V.

Педяш Никита Витальевич

ул. Нижняя Первомайская, д. 70, Москва 105203

Nikita V. Pedyash 

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

https://orcid.org/0000-0003-2974-1462ЗуевА. А.ZuevA. A.

Зуев Андрей Александрович, д.м.н., проф.

Scopus Author ID: 26424155600

ул. Нижняя Первомайская, д. 70, Москва 105203

Andrey A. Zuev, Dr. Sci. Med., Prof. 

Scopus Author ID: 26424155600

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

Федеральное государственное бюджетное учреждение «Национальный медико-хирургический центр им. Н.И. Пирогова» Министерства здравоохранения Российской ФедерацииРоссияPirogov National Medical and Surgical CenterRussian Federation202515012026174371383Copyright © Biyakaeva M.A., Gordeyeva E.A., Lukasheva A.D., Utyashev N.P., Utyasheva A.A., Pedyash N.V., Zuev A.A., 20262026Биякаева М.А., Гордеева Е.А., Лукашева А.Д., Утяшев Н.П., Утяшева А.А., Педяш Н.В., Зуев А.А.Biyakaeva M.A., Gordeyeva E.A., Lukasheva A.D., Utyashev N.P., Utyasheva A.A., Pedyash N.V., Zuev A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epilepsia.su/jour/article/view/1254Background

Background. Stereoelectroencephalography (stereo-EEG) parameters may be predictors of surgical treatment outcomes in patients with focal drug-resistant epilepsy (fDRE).

Objective

Objective: To assess a relationship between stereo-EEG parameters and surgical treatment for fDRE outcome.

Material and methods

Material and methods. The stereo-EEG parameters were retrospectively evaluated in fDRE patients examined in 2016–2020. We reviewed the following parameters: patient’s gender, age at stereo-EEG examination, lesion presence and lateralization on magnetic resonance images, seizure onset zone localization and size, seizure pattern type, latency and propagation. These parameter-related effect on surgical treatment outcomes in fDRE patients were analyzed.

Results

Results. The outcome of surgical treatment was found to depend on the size of epileptic seizure onset zone (p=0.002). No other analyzed parameters appeared to have an impact on epilepsy surgery outcome.

Conclusion

Conclusion. Size of seizure onset zone represent a sole stereo-EEG parameter affecting fDRE surgical treatment outcome.

Актуальность

Актуальность. Параметры стереоэлектроэнцефалографии (стерео-ЭЭГ) могут быть предикторами исхода хирургического лечения у пациентов с фокальной фармакорезистентной эпилепсией (ФФРЭ).

Цель

Цель: оценка взаимосвязи параметров стерео-ЭЭГ с исходом хирургического лечения ФФРЭ.

Материал и методы

Материал и методы. Ретроспективно oценены параметры стерео-ЭЭГ у пациентов, прошедших данное обследование за период 2016–2020 гг. В анализ включены следующие параметры: пол, возраст пациента на момент проведения стерео-ЭЭГ, наличие и латерализация структурной патологии на магнитно-резонансных томограммах, расположение и протяженность зоны инициации приступа, тип иктального паттерна, его латентность и пропагация. Проанализировано влияние данных факторов на исход хирургического лечения у пациентов с ФФРЭ.

Результаты

Результаты. Выявлена зависимость исхода хирургического лечения от размера зоны инициации эпилептического приступа (р=0,002). Остальные факторы, включенные в анализ, не продемонстрировали влияния на исход хирургического лечения ФФРЭ.

Заключение

Заключение. Единственным параметром стерео-ЭЭГ, оказывающим влияние на исход хирургического лечения ФФРЭ, является размер зоны инициации приступа.

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The authors declare that there are no conflicts of interest present.