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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">epilepsia</journal-id><journal-title-group><journal-title xml:lang="en">Epilepsy and paroxysmal conditions</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпилепсия и пароксизмальные состояния</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-8333</issn><issn pub-type="epub">2311-4088</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">epilepsia-159</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC SURVEYS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>CLINICAL LATERALIZING SIGNS IN SYMPTOMATIC TEMPORAL LOBE EPILEPSY</article-title><trans-title-group xml:lang="ru"><trans-title>КЛИНИЧЕСКИЕ ЛАТЕРАЛИЗАЦИОННЫЕ ПРИЗНАКИ ПРИ СИМПТОМАТИЧЕСКОЙ ВИСОЧНОЙ ЭПИЛЕПСИИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Мария Александровна – врач-невролог клиники. </p><p>Адрес: ул. Весенняя, д. 16. Первомайское пос., д. Пучково, Москва, Россия, 143397.</p><p> </p></bio><bio xml:lang="en"><p>Nikitina Marija Aleksandrovna – neurologist. </p><p>Address: Vesennyaya str., 16, Puchkovo vil., Moscow, Russia, 143397. </p></bio><email xlink:type="simple">womann19@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухин</surname><given-names>К. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukhin</surname><given-names>K. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мухин Константин Юрьевич – доктор медицинских наук, профессор, руководитель. </p><p>Адрес: ул. Весенняя, д. 16. Первомайское пос., д. Пучково, Москва, Россия, 143397.</p></bio><bio xml:lang="en"><p>Muhin Konstantin Jur'evich – MD, prof., the chief. </p><p>Address: Vesennyaya str., 16, Puchkovo vil., Moscow, Russia, 143397. </p></bio><email xlink:type="simple">center@epileptologist.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глухова</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Glukhova</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Глухова Лариса Юрьевна – кандидат медицинских наук, доцент, заведующая лабораторией сна и эпилепсии. </p><p>Адрес: ул. Весенняя, д. 16. Первомайское пос., д. Пучково, Москва, Россия, 143397.</p></bio><bio xml:lang="en"><p>Gluhova Larisa Jur'evna – PhD, ass. prof., head of the laboratory of sleep and epilepsy. </p><p>Address: Vesennyaya str., 16, Puchkovo vil., Moscow, Russia, 143397. </p></bio><email xlink:type="simple">center@epileptologist.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чадаев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chadaev</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чадаев Виктор Алексеевич – кандидат медицинских наук, доцент, заведующий лабораторией прехирургической диагностики эпилепсии. </p><p>Адрес: ул. Весенняя, д. 16. Первомайское пос., д. Пучково, Москва, Россия, 143397.</p></bio><bio xml:lang="en"><p>Chadaev Viktor Alekseevich – PhD, ass. prof., head of the laboratory diagnostics. </p><p>Address: Vesennyaya str., 16, Puchkovo vil., Moscow, Russia, 143397. </p></bio><email xlink:type="simple">center@epileptologist.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барлетова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Barletova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Барлетова Елена Игоревна – кандидат медицинских наук, врач-невролог клиники.</p><p>Адрес: ул. Весенняя, д. 16. Первомайское пос., д. Пучково, Москва, Россия, 143397.</p></bio><bio xml:lang="en"><p>Barletova Elena Igorevna – PhD. </p><p>Address: Vesennyaya str., 16, Puchkovo vil., Moscow, Russia, 143397. </p></bio><email xlink:type="simple">center@epileptologist.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт детской неврологии и эпилепсии имени Святителя Луки, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Luke’s institute of pediatric neurology and epilepsy, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт детской неврологии и эпилепсии имени Святителя Луки, Москва; &#13;
Российский национальный исследовательский медицинский университет имени Н.И. Пирогова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Luke’s institute of pediatric neurology and epilepsy, Moscow; &#13;
Pirogov Russian National Research Medical University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>11</day><month>06</month><year>2016</year></pub-date><volume>7</volume><issue>2</issue><fpage>59</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Nikitina M.A., Mukhin K.Y., Glukhova L.Y., Chadaev V.A., Barletova E.I., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Никитина М.А., Мухин К.Ю., Глухова Л.Ю., Чадаев В.А., Барлетова Е.И.</copyright-holder><copyright-holder xml:lang="en">Nikitina M.A., Mukhin K.Y., Glukhova L.Y., Chadaev V.A., Barletova E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epilepsia.su/jour/article/view/159">https://www.epilepsia.su/jour/article/view/159</self-uri><abstract><p>The article presents a review of world literature on significance of various clinical lateralizing signs in temporal lobe epilepsy, such as dystonic posturing, limb automatisms, ictal and postictal aphasia, ictal nystagmus, head turning, periiktal headache, etc. The results of current research are compared with previously published reports. The ictal dystonic unilateral limb posturing (possibly isolated in a hand, foot, predominantly in distal parts of limbs) is still one of the most informative lateralizing signs and it is lateralized in contralateral hemisphere in 100% of cases. It is shown that the "early" and "late" head turning, and unilateral limb automatisms are the most important and convincing lateralizing signs, which must be considered in connection with the EEG data to determine the epileptogenic focus in patients with temporal lobe epilepsy.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены данные мировой литературы о значении различных клинических латерализационных признаков при височной эпилепсии, таких как дистоническая установка, автоматизмы, иктальная и постиктальная афазия, иктальный нистагм, адверсия головы, перииктальная головная боль и др. Результаты современных исследований сопоставлены с ранее опубликованными сообщениями. Одним из наиболее информативных латерализационных признаков по-прежнему остается иктальная односторонняя дистоническая установка в конечностях (возможно изолированно в руке, ноге, преимущественно в дистальных отделах), которая латерализована в контралатеральной очагу гемисфере в 100% случаев. Показано, что «ранняя» и «поздняя» адверсии головы и унилатеральные кистевые автоматизмы в конечностях также являются важнейшими и достаточно убедительными латерализационными признаками, которые следует рассматривать в сочетании с ЭЭГ-данными для определения эпилептогенного фокуса у больных с височной эпилепсией. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>височная эпилепсия</kwd><kwd>латерализация</kwd><kwd>видео-ЭЭГ-мониторинг</kwd><kwd>ЭЭГ</kwd><kwd>семиология приступов</kwd><kwd>парциальные приступы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>temporal lobe epilepsy</kwd><kwd>lateralization</kwd><kwd>video-EEG monitoring</kwd><kwd>EEG</kwd><kwd>seizure semiology</kwd><kwd>partial seizures</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бояринцева С.Е., Клушин Д.Ф. 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