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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">epilepsia</journal-id><journal-title-group><journal-title xml:lang="en">Epilepsy and paroxysmal conditions</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпилепсия и пароксизмальные состояния</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-8333</issn><issn pub-type="epub">2311-4088</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">epilepsia-21</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group></article-categories><title-group><article-title>CLINICAL FEATURES OF FOCAL EPILEPSY WITH SECONDARY BILATERAL SYNCHRONIZATION ON EEG AMONG ADOLESCENTS</article-title><trans-title-group xml:lang="ru"><trans-title>ОСОБЕННОСТИ КЛИНИЧЕСКИХ ПРОЯВЛЕНИЙ ФОКАЛЬНОЙ ЭПИЛЕПСИИ С ПАТТЕРНОМ ВТОРИЧНОЙ БИЛАТЕРАЛЬНОЙ СИНХРОНИЗАЦИИ НА ЭЭГ У ПОДРОСТКОВ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Садыков</surname><given-names>Т. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Sadykov</surname><given-names>T. R.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Генералов</surname><given-names>В. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Generalov</surname><given-names>V. O.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казакова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazakova</surname><given-names>Yu. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр внедрения передовых медицинских технологий «Планета Мед», Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Centre of adoption of modern medical technologies «Planeta Med», Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State scientific and clinical centre of child hematology, oncology and immunology by the name of Dmitry Rogachev, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>31</day><month>05</month><year>2016</year></pub-date><volume>5</volume><issue>1</issue><fpage>42</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Sadykov T.R., Rumyantsev A.G., Generalov V.O., Kazakova Y.V., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Садыков Т.Р., Румянцев А.Г., Генералов В.О., Казакова Ю.В.</copyright-holder><copyright-holder xml:lang="en">Sadykov T.R., Rumyantsev A.G., Generalov V.O., Kazakova Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epilepsia.su/jour/article/view/21">https://www.epilepsia.su/jour/article/view/21</self-uri><abstract><p>Abstract: current work is dedicated to analysis of features of clinical and encephalographic manifestations of focal epilepsy with secondary bilateral synchronization on EEG and onset in adolescence. The other aim was comparison these findings among patients with onset in adolescents and adult patients. We analyzed data of 66 adolescent patients and 61 adult patients with focal epilepsy with secondary bilateral synchronization on EEG. All patients were investigated with prolonged videoencephalographic monitoring and MRI of the brain. Analysis of types of epileptic seizures was made too. We revealed that etiological factor of focal epilepsy with secondary bilateral synchronization on EEG could not be found in case of onset of epilepsy in adolescence in contrast to epilepsy with onset in adult age. Secondary generalized convulsive seizures with fast generalization, bilateral myoclonic seizures and dialeptic seizures were more appropriate for focal epilepsy with secondary bilateral synchronization on EEG in case of onset of epilepsy in adolescence than for epilepsy with onset in adult age. Moreover focal epilepsy with secondary bilateral synchronization on EEG in case of onset in adolescence can form phonotypical copies of idiopathic generalized forms of epilepsy.</p></abstract><trans-abstract xml:lang="ru"><p>В статье проводится исследование особенностей клинической картины и энцефалографических проявлений фокальной эпилепсии с паттерном вторичной билатеральной синхронизации (ВБС) на энцефалограмме (ЭЭГ) при дебюте заболевания в подростковом возрасте и сравнение их с таковыми при дебюте в молодом взрослом возрасте. Проанализированы данные 66 пациентов подросткового возраста и 61 пациента молодого взрослого возраста, страдавших фокальной эпилепсией с паттерном ВБС на ЭЭГ. Все пациентам проведен анализ семиологии эпилептических приступов, ночной видеоэнцефалографический мониторинг, магнитно-резонансная томография головного мозга. Выявлено, что для фокальной эпилепсии с паттерном ВБС на ЭЭГ в случае дебюта в подростковом возрасте более характерно отсутствие этиологического фактора возникновения эпилепсии, наличие в клинической картине вторично-генерализованных судорожных приступов с быстрой клинической генерализацией, билатеральных миоклоний, диалептических абсансоподобных приступов. Кроме этого, выявлена возможность формирования фенотипических копий идиопатических генерализованных эпилепсий в виде фокальной эпилепсии с паттерном ВБС на ЭЭГ.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Эпилепсия</kwd><kwd>вторичная билатеральная синхронизация</kwd><kwd>видеоэнцефалографический мониторинг</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>secondary bilateral synchronization</kwd><kwd>videoencephalographic monitoring</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Agostini M.A., Garcia M.C., Diaz-Arrastia R. et al. Clinical, electroencephalographic and neuroradiologic characteristics of secondary bilateral synchrony in localization-related epilepsy. Epilepsia. 2002; 43 (7): 34 p.</mixed-citation><mixed-citation xml:lang="en">Agostini M.A., Garcia M.C., Diaz-Arrastia R. et al. 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