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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">epilepsia</journal-id><journal-title-group><journal-title xml:lang="en">Epilepsy and paroxysmal conditions</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпилепсия и пароксизмальные состояния</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-8333</issn><issn pub-type="epub">2311-4088</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">epilepsia-22</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group></article-categories><title-group><article-title>LAMOTRIGINE USE IN THE TREATMENT OF EPILEPSY IN ELDERLY PATIENTS</article-title><trans-title-group xml:lang="ru"><trans-title>ОПЫТ ПРИМЕНЕНИЯ ЛАМОТРИДЖИНА ПРИ ЛЕЧЕНИИ ЭПИЛЕПСИИ У ПОЖИЛЫХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурмухаметова</surname><given-names>С. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurmuhametova</surname><given-names>S. R.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магжанов</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Magzhanov</surname><given-names>R. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет, Уфа; Республиканская клиническая больница имени Г.Г. Куватова, Уфа</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Bashkir state medical university, Ufa; G.G. Kuvatova Republican clinical hospital, Ufa</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>31</day><month>05</month><year>2016</year></pub-date><volume>5</volume><issue>1</issue><fpage>48</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Nurmuhametova S.R., Magzhanov R.V., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Нурмухаметова С.Р., Магжанов Р.В.</copyright-holder><copyright-holder xml:lang="en">Nurmuhametova S.R., Magzhanov R.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epilepsia.su/jour/article/view/22">https://www.epilepsia.su/jour/article/view/22</self-uri><abstract><p>Abstract: epilepsy is 3d common neurologic problem after cerebrovascular diseases and dementia in elderly patients. At the onset of epilepsy in elderly patients the most frequent etiologic factors are cerebrovascular, neurodegenerativ diseases, neurosurgical pathology. About 25 % of epilepsy cases in elderly patients are related to idiopathic epilepsy. In elderly people all type of seizures can be observed. In the international recommend ations on the treatment of elderly patients with focal seizures gabapentin, lamotrigine, carbamazepine are used. Lamotrigine is used as first line therapy of epilepsy in elderly patients in monotherapy or combined drug therapy.</p></abstract><trans-abstract xml:lang="ru"><p>У больных пожилого возраста эпилепсия является третьей по частоте неврологической проблемой после цереброваскулярных заболеваний и деменции. При начале эпилепсии в старшей возрастной группе наиболее частыми этиологическими факторами эпилепсии являются цереброваскулярные и нейродегенеративные заболевания, нейрохирургическая патология. Около 25% случаев впервые возникшей эпилепсии у пациентов пожилого возраста относится к идиопатической эпилепсии. У пожилых могут наблюдаться все типы приступов. В международных рекомендациях по лечению пациентов пожилого возраста с парциальными припадками указываются габапентин, ламотриджин, карбамазепин. Препараты группы ламотриджина являются препаратами первой линии выбора в лечении эпилепсии у пожилых пациентов как в качестве монотерапии, так и при комбинированной терапии в качестве базового препарата.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Эпилепсия</kwd><kwd>пожилые</kwd><kwd>ламотриджин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>elderly patients</kwd><kwd>lamotrigine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гехт А.Б. Фармакотерапия эпилепсии у больных пожилого возраста / А.Б. Гехт, Э.Г. Меликян, Ф.К. Дзугаева и др. 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