epilepsiaEpilepsy and paroxysmal conditionsЭпилепсия и пароксизмальные состояния2077-83332311-4088IRBIS LLCepilepsia-257Research ArticleSCIENTIFIC SURVEYSНАУЧНЫЕ ОБЗОРЫROLE OF TOPIRAMATE IN TREATMENT OF EPILEPSYРОЛЬ ТОПИРАМАТА В ЛЕЧЕНИИ ЭПИЛЕПСИИБурдС. Г.BurdS. G.ГБОУ ВПО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздравсоцразвития России (Москва)РоссияThe Russian State Medical University named after N.I. Pirogov (Moscow)Russian Federation201201092016413439Copyright © Burd S.G., 20162016Бурд С.Г.Burd S.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epilepsia.su/jour/article/view/257

The review summarizes modern data on efficacy, safety and role of topiramate in treatment of epilepsy. Pharmacokinetic and pharmacodynamiccharacteristics of the medicine are presented in the article. The role of topiramate in epilepsy treatment with accounts to its pharmacoenomic values and modern requirements to antiepileptic drugs is determined. Based on presented data conclusion on topiramate efficacy in treatment of various forms of epilepsy in children and adults used both in mono- as well as in combined therapy can be done.

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The authors declare that there are no conflicts of interest present.