epilepsiaEpilepsy and paroxysmal conditionsЭпилепсия и пароксизмальные состояния2077-83332311-4088IRBIS LLCepilepsia-283Research ArticleORIGINAL ARTICLESОРИГИНАЛЬНЫЕ СТАТЬИBRAIN BLOOD FLOW EXAMINATION WITH HIGH-FLOOR MRI-PERFUSION DURING THE ATTACK OF MIGRAINE WITHOUT AURAИССЛЕДОВАНИЕ МОЗГОВОГО КРОВОТОКА С ПОМОЩЬЮ ВЫСОКОПОЛЬНОЙ МРТ-ПЕРФУЗИИ ВО ВРЕМЯ ПРИСТУПА МИГРЕНИ БЕЗ АУРЫКорешкинаМ. И.KoreshkinaM. I.ХаликовА. Д.KhalikovA. D.НазинкинаЮ. В.NazinkinaYu. V.ОсиповаВ. В.OsipovaV. V.АмелинА. В.AmelinA. V.КосмачеваЕ. А.KosmachevaE. A.Центр лечения головной боли клиники «Скандинавия» (ООО «АВА-ПЕТЕР»), Санкт-ПетербургРоссияCenter of treatment of headache. «Scandinavia» clinic (ООО «AVA-PETER»), Saint-PetersburgRussian FederationООО «международная клиника MEDEM», СПбГМА им. И.И. Мечникова, Санкт-ПетербургРоссияООО «International clinic MEDEM», STbSMA n.a. I.I. Mechnikov, Saint-PetersburgRussian FederationИнститут мозга человека РАН, Санкт-ПетербургРоссияInstitute of Human Brain Russian Academy of Science, Saint-PetersburgRussian FederationНИЦ Первого МГМУ им. И.М. Сеченова; Российское общество по изучению головной боли (РОИГБ), МоскваРоссияScientific Investigational Center of First MSMU n.a. I.M. Sechenov; Russian Society of Headache Investigation, MoscowRussian FederationСанкт-Петербургский государственный медицинский университет им. акад. И.П. ПавловаРоссияSaint-Petersburg State Medical University n.a. I.P. PavlovRussian FederationМеждународный медицинский центр «СОГАЗ», Санкт-ПетербургРоссияInternational Medical Center «Sogaz», Saint-PetersburgRussian Federation201207092016441217Copyright © Koreshkina M.I., Khalikov A.D., Nazinkina Y.V., Osipova V.V., Amelin A.V., Kosmacheva E.A., 20162016Корешкина М.И., Халиков А.Д., Назинкина Ю.В., Осипова В.В., Амелин А.В., Космачева Е.А.Koreshkina M.I., Khalikov A.D., Nazinkina Y.V., Osipova V.V., Amelin A.V., Kosmacheva E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epilepsia.su/jour/article/view/283

The main goal of our study was to gain knowledge on blood supply changes during an attack in patients with migraine without aura using contrast-enhanced perfusion-weighted MRI (PWI). Standard MRI, and PWI were performed twice: during an attack (in all three cases) and in between attacks (in two cases). Three females with long history of migraine without aura were observed. Cerebral blood volume (CBV), mean transit time of the contrast bolus (MTT), and cerebral blood flow (CBF) were calculated using Functool package. All three cases produced similar local MR perfusion changes that included reduced CBV and decreased CBF without any change in MTT. Cerebral blood supply decrease observed during migraine attack is reversible and absent during headache-free interval. Transient perfusion abnormalities occurring during recurrent attacks and confirmed by PWI may serve as one of the mechanisms causing the small subcortical white matter lesions.

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The authors declare that there are no conflicts of interest present.