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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">epilepsia</journal-id><journal-title-group><journal-title xml:lang="en">Epilepsy and paroxysmal conditions</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпилепсия и пароксизмальные состояния</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-8333</issn><issn pub-type="epub">2311-4088</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">epilepsia-287</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group></article-categories><title-group><article-title>EXPERIENCE OF TREATMENT WITH GENERIC LAMOTRIDJIN IN DIFFERENT FORMS OF EPILEPSY (The results of focus observation in out-patient clinics network of Moscow city public healthcare services)</article-title><trans-title-group xml:lang="ru"><trans-title>ОПЫТ ПРИМЕНЕНИЯ ГЕНЕРИЧЕСКОГО ЛАМОТРИДЖИНА ПРИ РАЗЛИЧНЫХ ФОРМАХ ЭПИЛЕПСИИ (результаты фокусного наблюдения в учреждениях амбулаторной сети городского здравоохранения г. Москвы)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадалян</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Badalyan</surname><given-names>O. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богомазова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogomazova</surname><given-names>M. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавлева</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravleva</surname><given-names>I. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исмаилов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ismailov</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артемова</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>.</surname><given-names>.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комелькова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Komelkova</surname><given-names>E. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лесинкер</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lesinker</surname><given-names>L. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Логвинов</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Logvinov</surname><given-names>Yu. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Отческая</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Otcheskaya</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>S. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соломатин</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Solomatin</surname><given-names>Yu. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Теплышева</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Teplysheva</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Удовиченко</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Udovuchenko</surname><given-names>T. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хромых</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khromykh</surname><given-names>A. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чуканова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Chukanova</surname><given-names>A. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурд</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Burd</surname><given-names>S. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бойко</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Boiko</surname><given-names>A. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городские поликлиники г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City polyclinics, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО РНИМУ им. Н.И. Пирогова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>GBOU VPO RNIMU named after N.I. Pirogov, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>07</day><month>09</month><year>2016</year></pub-date><volume>4</volume><issue>4</issue><fpage>40</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Badalyan O.L., Bogomazova M.A., Zhuravleva I.I., Ismailov A.M., . ..Ю., Komelkova E.G., Lesinker L.N., Logvinov Y.I., Otcheskaya O.V., Petrov S.V., Solomatin Y.V., Teplysheva A.M., Udovuchenko T.N., Khromykh A.E., Chukanova A.S., Lebedeva A.V., Burd S.G., Boiko A.N., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Бадалян О.Л., Богомазова М.А., Журавлева И.И., Исмаилов А.М., Артемова И.Ю., Комелькова Е.Г., Лесинкер Л.Н., Логвинов Ю.И., Отческая О.В., Петров С.В., Соломатин Ю.В., Теплышева А.М., Удовиченко Т.Н., Хромых Е.А., Чуканова А.С., Лебедева А.В., Бурд С.Г., Бойко А.Н.</copyright-holder><copyright-holder xml:lang="en">Badalyan O.L., Bogomazova M.A., Zhuravleva I.I., Ismailov A.M., . .., Komelkova E.G., Lesinker L.N., Logvinov Y.I., Otcheskaya O.V., Petrov S.V., Solomatin Y.V., Teplysheva A.M., Udovuchenko T.N., Khromykh A.E., Chukanova A.S., Lebedeva A.V., Burd S.G., Boiko A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epilepsia.su/jour/article/view/287">https://www.epilepsia.su/jour/article/view/287</self-uri><abstract><p>Focused observational study on efficacy, tolerability and quality of life in adult patients with different forms of epilepsy taking combined therapy with lamotrigine (Sazar). 32 patients (19 men and 13 women), 23-79 years old with focal forms (cryptogenic and symptomatic) epilepsy with different disease duration and presence of of different type and etiology seizures were enrolled into the study. Patients having been taken various antiepileptic drugs in monotherapy with different efficacy degree were observed. Patients sample included 20 patients, receiving valproic acid in various dosages and 12 patients, receiving topiramate. Sazar was added as a second drug with initial dosage of 25 mg daily. Results of focused observation allow us to make conclusion of possible expedience of Sazar indication, especially in patients in whom therapy with valproic acid is less effective.</p></abstract><trans-abstract xml:lang="ru"/><kwd-group xml:lang="ru"><kwd>эпилепсия</kwd><kwd>комбинированная терапия</kwd><kwd>ламотриджин</kwd><kwd>Сейзар</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epilepsy</kwd><kwd>combined therapy</kwd><kwd>lamotrigine</kwd><kwd>Sazar.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дробижев М.Ю. 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