epilepsiaEpilepsy and paroxysmal conditionsЭпилепсия и пароксизмальные состояния2077-83332311-4088IRBIS LLC10.17749/2077-8333.2017.9.4.050-063epilepsia-371Research ArticleSCIENTIFIC SURVEYSНАУЧНЫЕ ОБЗОРЫTHE IMPACT OF EPILEPTIC SEIZURES ON THE HEART RHYTHM AND CONDUCTION: A REVIEW ARTICLEВЛИЯНИЕ ЭПИЛЕПТИЧЕСКИХ ПРИСТУПОВ НА СЕРДЕЧНЫЙ РИТМ И ПРОВОДИМОСТЬ: ЛИТЕРАТУРНЫЙ ОБЗОРРублёваЮ. В.RublevaYu. V.

Рублёва Юлия Владимировна – аспирант.

117997, Москва, ул. Островитянова, д. 1

Rubleva Yulia Vladimirovna – Postgraduate MD, the Pirogov Russian National Medical University.

Ul. Ostrovityanova, 1, Moscow, 117997

julia2105@rambler.ruМироновМ. Б.MironovM. B.

Миронов Михаил Борисович – кандидат медицинских наук, доцент кафедры клинической физиологии и функциональной диагностики.

Волоколамское шоссе, д. 91, Москва, 125371

Mironov Mikhail Borisovich – MD, PhD, Associate Prof. at the Department of clinical physiology and functional diagnostics.

Volokolamskoe s., 91, Moscow, 125371

mironovmb@mail.ruКрасильщиковаТ. М.KrasilshchikovaT. M.

Красильщикова Татьяна Михайловна – ассистент кафедры неврологии, нейрохирургии и медицинской генетики педиатрического факультета.

Krasil’shchikova Tat’yana Mikhailovna – MD, Assistant professor of neurology, neurosurgery and medical genetics, Faculty of Pediatrics.

Ul. Ostrovityanova, 1, Moscow, 117997

БурдС. Г.BurdS. G.

Бурд Сергей Георгиевич – доктор медицинских наук, профессор кафедры неврологии, нейрохирургии и медицинской генетики лечебного факультета.

Burd Sergei Georgievich – MD, Professor of neurology, neurosurgery and medical genetics, Faculty of Medicine.

Ul. Ostrovityanova, 1, Moscow, 117997

burds@yandex.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Министерства здравоохранения Российской ФедерацииРоссияN. I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaRussian FederationФедеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Институт повышения квалификации Федерального медико-биологического агентства»РоссияThe Institute of advanced training of Federal medical-biological AgencyRussian Federation201722022018945063Copyright © Rubleva Y.V., Mironov M.B., Krasilshchikova T.M., Burd S.G., 20182018Рублёва Ю.В., Миронов М.Б., Красильщикова Т.М., Бурд С.Г.Rubleva Y.V., Mironov M.B., Krasilshchikova T.M., Burd S.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epilepsia.su/jour/article/view/371

Epileptic seizures affect the heart function and can provoke heart rhythm abnormalities and conduction disorders. Dysfunctions of the supra-segmental vegetative structures are thought to play a significant role in the development of arrhythmic syndrome in epilepsy. The asymmetric influence of the left and right cerebral hemispheres on the heart rate, the impact of antiepileptic drugs and other factors on the heart rhythm are still under discussion. The role of heart rhythm abnormalities in the pathogenesis of sudden unexplained death in epilepsy is also reviewed here. We analyze the pathogenesis of cardiac arrhythmias in epilepsy, the occurrence and risk factors, the types of disorders, the role of antiepileptic therapy and the significance of cardiac arrhythmias for the development of sudden death in patients with epilepsy (SUDEP).

Эпилептические приступы влияют на функцию сердца и могут вызывать нарушения сердечного ритма и проводимости. Основную роль в возникновении аритмического синдрома при эпилепсии отводят дисфункции надсегментарных вегетативных образований. Асимметричное влияние левого и правого полушарий головного мозга на частоту сердечных сокращений, влияние противоэпилептических препаратов и других факторов на сердечный ритм все еще находятся в стадии обсуждения. Также обсуждается роль нарушений ритма сердца в патогенезе внезапной необъяснимой смерти при эпилепсии. Мы рассматриваем патогенетические механизмы нарушений ритма сердца при эпилепсии, факторы риска, их частоту возникновения, типы нарушений, роль противоэпилептической терапии и их значение в механизмах развития внезапной смерти больных эпилепсией (Sudden unexpected death in epilepsy, SUDEP).

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The authors declare that there are no conflicts of interest present.