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<article article-type="editorial" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">epilepsia</journal-id><journal-title-group><journal-title xml:lang="en">Epilepsy and paroxysmal conditions</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпилепсия и пароксизмальные состояния</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-8333</issn><issn pub-type="epub">2311-4088</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2077-8333/epi.par.con.2021.093</article-id><article-id custom-type="elpub" pub-id-type="custom">epilepsia-734</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EVENTS</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СОБЫТИЯ</subject></subj-group></article-categories><title-group><article-title>Effectiveness, safety and assessing the results of drug therapy in patients with epilepsy</article-title><trans-title-group xml:lang="ru"><trans-title>Об эффективности, безопасности и оценке результатов лекарственной терапии больных эпилепсией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Редакционная</surname><given-names>статья</given-names></name><name name-style="western" xml:lang="en"><surname>Editorial</surname><given-names>Article</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>29</day><month>10</month><year>2021</year></pub-date><volume>13</volume><issue>3</issue><fpage>306</fpage><lpage>310</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Editorial a., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Редакционная с.</copyright-holder><copyright-holder xml:lang="en">Editorial a.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epilepsia.su/jour/article/view/734">https://www.epilepsia.su/jour/article/view/734</self-uri><abstract><p>On June 26, 2021, a meeting of the experts of the Russian League Against Epilepsy (RLAE) was held, dedicated to the effectiveness, safety and assessing the results of drug therapy in patients with epilepsy. Having considered the history of the issue and guided by domestic and foreign experience, the participants discussed the problems associated with the use of various antiepileptic drugs for different forms of epilepsy in patients of different sex and age. Special attention was paid to psychiatric comorbidity in patients with epilepsy, increasing their compliance with treatment and quality of life. The article presents the Resolution of RLAE experts meeting adopted as a result of the discussion.</p></abstract><trans-abstract xml:lang="ru"><p>26 июня 2021 г. состоялось заседание экспертов Российской Противоэпилептической Лиги (РПЭЛ), посвященное теме эффективности, безопасности и оценки результатов лекарственной терапии больных эпилепсией. Рассмотрев историю вопроса и руководствуясь отечественным и зарубежным опытом, участники обсудили проблемы, связанные с использованием различных противоэпилептических препаратов при разных формах эпилепсии у пациентов разного пола и возраста. Особое внимание было уделено психиатрической коморбидности у больных эпилепсией, повышению приверженности лечению и качества жизни пациентов. В статье представлена Резолюция заседания экспертов РПЭЛ, принятая в результате дискуссии.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Эпилепсия</kwd><kwd>эффективность терапии</kwd><kwd>безопасность терапии</kwd><kwd>оценка результатов терапии</kwd><kwd>противоэпилептические препараты</kwd><kwd>ламотриджин</kwd><kwd>клинические исследования</kwd><kwd>переносимость препарата</kwd><kwd>психиатрическая коморбидность</kwd><kwd>приверженность лечению</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Epilepsy</kwd><kwd>effectiveness of therapy</kwd><kwd>safety of therapy</kwd><kwd>assessing therapy results</kwd><kwd>antiepileptic drugs</kwd><kwd>lamotrigine</kwd><kwd>clinical studies</kwd><kwd>drug tolerability</kwd><kwd>psychiatric comorbidity</kwd><kwd>compliance with treatment</kwd><kwd>quality of life</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Публикация подготовлена при финансовой поддержке компании «Алкалоид». Авторы несут полную ответственность за содержание публикации и редакционные решения</funding-statement><funding-statement xml:lang="en">This article was published with the financial support of Alkaloid company. The authors are fully responsible for the content of the article and editorial decisions.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shorvon S.D. Drug treatment of epilepsy in the century of the ILAE: the first 50 years, 1909–1958. Epilepsia. 2009; 50 (Suppl. 3): 69–92. https://doi.org/10.1111/j.1528-1167.2009.02041.x.</mixed-citation><mixed-citation xml:lang="en">Shorvon S.D. Drug treatment of epilepsy in the century of the ILAE: the first 50 years, 1909–1958. 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