epilepsiaEpilepsy and paroxysmal conditionsЭпилепсия и пароксизмальные состояния2077-83332311-4088IRBIS LLC10.17749/2077-8333/epi.par.con.2022.115epilepsia-775Research ArticleSCIENTIFIC SURVEYSНАУЧНЫЕ ОБЗОРЫNeurological disorders after hysterectomy: from pathogenesis to clinical manifestationsНеврологические расстройства после гистерэктомии: от патогенеза к клиникеhttps://orcid.org/0000-0002-7456-2386СолоповаА. Г.SolopovaA. G.

Солопова Антонина Григорьевна – доктор медицинских наук, профессор  кафедры акушерства и гинекологии Клинического института детского здоровья  им. Н.Ф. Филатова.

ул. Большая Пироговская, д. 2, стр. 4, Москва 119991.

Scopus Author ID: 6505479504

WoS Researcher ID: Q-1385-2015

РИНЦ SPIN-код: 5278-0465

Antonina G. Solopova – Dr. Med. Sc., Professor, Chair of Obstetrics and Gynecology, Filatov Clinical Institute of Children's Health, Sechenov University.

2 bldg 4 Bolshaya Pirogovskaya Str., Moscow 119991.

Scopus   Author ID: 6505479504

WoS Researcher ID: Q-1385-2015

RSCI SPIN-code: 5278-0465

antoninasolopova@yandex.ruhttps://orcid.org/0000-0002-3367-9844БлиновД. В.BlinovD. V.

Блинов Дмитрий Владиславович – кандидат медицинских наук, руководитель по научным и медицинским вопросам ИПСОМ; врач-невролог Клинического госпиталя «Лапино» ГК «Мать и дитя».

ул. Садовая-Триумфальная, д. 4/10, Москва 127006; 1-е Успенское ш., д. 111, Московская обл., Одинцовский р-н, Лапино 143081.

WoS ResearcherID:  E-8906-2017

Scopus  Author ID: 6701744871

РИНЦ SPIN-код: 9779-8290

Dmitry V. Blinov – MD, PhD, MBA, Head of Medical and Scientific Affairs, Institute for Preventive and Social Medicine; Neurologist, Lapino Clinic Hospital, MG “Mother and Child”.

4/10 Sadovaya-Triumfalnaya Str., Moscow 127006; 111 Pervoye Uspenskoye Hwy, Moscow  Region, Odintsovo District, Lapino 143081.

WoS ResearcherID: E-8906-2017

Scopus Author ID: 6701744871

RSCI SPIN-code: 9779-8290

https://orcid.org/0000-0003-2275-2257БеговичЁ.BegovichE.

Бегович Ёвана – аспирант кафедры акушерства и гинекологии Клинического института детского  здоровья  им. Н.Ф. Филатова.

ул. Большая Пироговская, д. 2, стр. 4, Москва 119991.

Evana Begovich – Postgraduate,  Chair of Obstetrics and Gynecology, Filatov Clinical Institute of Children's Health, Sechenov University.

2 bldg 4 Bolshaya Pirogovskaya Str., Moscow 119991.

https://orcid.org/0000-0002-5083-6581СанджиеваЛ. Н.SandzhievaL. N.

Санджиева  Лидия  Николаевна  – аспирант  кафедры  акушерства  и гинекологии  Клинического  института  детского здоровья  им. Н.Ф. Филатова.

ул. Большая Пироговская, д. 2, стр. 4, Москва 119991.

РИНЦ SPIN-код: 7228-3726

Lidiya N Sandzhieva – Postgraduate,  Chair of Obstetrics and Gynecology, Filatov Clinical Institute of Children's Health, Sechenov University.

2 bldg 4 Bolshaya Pirogovskaya Str., Moscow 119991.

RSCI SPIN-code: 7228-3726

https://orcid.org/0000-0002-1893-7198ДемьяновС. В.DemyanovS. V.

Демьянов Семен Валерьевич – студент 5-го курса.

ул. Большая Пироговская, д. 2, стр. 4, Москва 119991.

Semen V. Demyanov – 5th Year Student, Sechenov  University.

2 bldg 4 Bolshaya Pirogovskaya Str., Moscow 119991.

https://orcid.org/0000-0003-1584-4604ДемьяновГ. В.DemyanovG. V.

Демьянов Глеб Валерьевич – студент 5-го курса.

ул. Большая Пироговская, д. 2, стр. 4, Москва 119991.

Gleb V. Demyanov – 5th Year Student, Sechenov  University.

2 bldg 4 Bolshaya Pirogovskaya Str., Moscow 119991.

Первый Московский государственный медицинский университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)РоссияSechenov UniversityRussian FederationИнститут Превентивной и Социальной Медицины; Клинический госпиталь «Лапино» группы компаний «Мать и Дитя»РоссияInstitute for Preventive and Social Medicine; Lapino Clinical Hospital, Medical Group “Mother and Child”Russian Federation2022170420221415464Copyright © Solopova A.G., Blinov D.V., Begovich E., Sandzhieva L.N., Demyanov S.V., Demyanov G.V., 20222022Солопова А.Г., Блинов Д.В., Бегович Ё., Санджиева Л.Н., Демьянов С.В., Демьянов Г.В.Solopova A.G., Blinov D.V., Begovich E., Sandzhieva L.N., Demyanov S.V., Demyanov G.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.epilepsia.su/jour/article/view/775

Hysterectomy currently occupies one of the leading places among obstetric and gynecological surgeries and is one of the highly effective and sometimes the only method of treating various diseases of the female genital organs.  Quite often, however, hysterectomy results not only in the elimination of the cause of disease, but also in the development of complications that reduce the quality of life of patients. More and more attention is being paid to neurological complications, which is obviously due to improved diagnostic capabilities, as well as the results of recent research on the pathogenesis and treatment of neurological disorders. Only recently the scientists have begun to think about the true causes  of one of the most important neurologic complications of hysterectomy, namely chronic postoperative pain.

The review describes in detail the main neurological disorders that develop after hysterectomy: chronic postoperative pain, traumatic neuroma, residual ovarian syndrome  as possible causes of chronic pain, mononeuropathies, sexual and sleep disorders, decreased cognitive and motor functions, lower  urinary tract and bowel dysfunction.  Considerable  attention is given to the mechanisms of neurological complications and the relationship between the surgery and emotional disturbances in women.

В настоящее время гистерэктомия занимает одно  из ведущих мест среди акушерско-гинекологических  операций и является одним из высокоэффективных,  а иногда и единственным методом  лечения различных заболеваний женских половых органов. Однако довольно часто результатом гистерэктомии становится не только устранение причины болезни,  но и развитие осложнений,  снижающих качество  жизни пациенток. Все большее  внимание привлекают к себе неврологические осложнения, что, очевидно, связано с улучшением качества диагностических возможностей,  а  также результатами последних  исследований  в области  изучения патогенеза  и лечения неврологических  расстройств.  Так, лишь недавно ученые стали задумываться  об истинных причинах одного  из самых важных неврологических осложнений гистерэктомии, а именно хронической послеоперационной  боли.

В обзоре  подробно описаны основные неврологические расстройства, развивающиеся после гистерэктомии: хроническая послеоперационная боль, травматическая неврома и синдром остаточных яичников как возможные  причины появления хронической  боли,  мононевропатия,  расстройства  сексуальной  функции и сна, снижение когнитивных и двигательных функций, дисфункции  нижних мочевыводящих  путей и кишечника. Значительное место  отведено механизмам развития неврологических осложнений и взаимосвязи  операции с нарушением эмоционального  фона у женщин.

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The authors declare that there are no conflicts of interest present.