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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">epilepsia</journal-id><journal-title-group><journal-title xml:lang="en">Epilepsy and paroxysmal conditions</journal-title><trans-title-group xml:lang="ru"><trans-title>Эпилепсия и пароксизмальные состояния</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-8333</issn><issn pub-type="epub">2311-4088</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2077-8333/epi.par.con.2023.168</article-id><article-id custom-type="elpub" pub-id-type="custom">epilepsia-928</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group></article-categories><title-group><article-title>Algorithm for the provision of comprehensive psychotherapeutic support to women experiencing neuropsychiatric symptoms during rehabilitation following the treatment of malignant neoplasms of the reproductive system</article-title><trans-title-group xml:lang="ru"><trans-title>Алгоритм комплексной психотерапевтической поддержки для женщин с психоневрологическими симптомами в период реабилитации после лечения злокачественных новообразований репродуктивной системы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3367-9844</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блинов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Blinov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блинов Дмитрий Владиславович – к.м.н., ассистент кафедры спортивной медицины и медицинской реабилитации Института клинической медицины им. Н.В. Склифосовского; руководитель по медицинским и научным вопросам; доцент кафедры спортивной, физической и реабилитационной медицины</p><p>Scopus Author ID: 6701744871; WoS Researcher ID: E-8906-2017</p><p>ул. Большая Пироговская, д. 2, стр. 4, Москва 119991</p><p>ул. Садовая-Триумфальная, д. 4/10, Москва 127006</p><p>ул. 2-я Брестская, д. 5, стр. 1-1а, Москва 123056</p></bio><bio xml:lang="en"><p>Dmitry V. Blinov – MD, PhD, MBA, Assistant Professor, Chair of Sports Medicine and Medical Rehabilitation; Head of Medical and Scientific Affairs; Associate Professor, Chair of Sports, Physical and Rehabilitation Medicine</p><p>Moscow</p><p>Scopus Author ID: 6701744871; WoS Researcher ID: E-8906-2017</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7456-2386</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солопова</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Solopova</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Солопова Антонина Григорьевна – д.м.н., профессор кафедры акушерства, гинекологии и перинатальной медицины Клинического института детского здоровья им. Н.Ф. Филатова</p><p>Scopus Author ID: 6505479504; WoS Researcher ID: Q-1385-2015</p><p>ул. Большая Пироговская, д. 2, стр. 4, Москва 119991</p></bio><bio xml:lang="en"><p>Antonina G. Solopova – Dr. Med. Sc., Professor, Chair of Obstetrics, Gynecology and Perinatal Medicine, Filatov Clinical Institute of Children's Health</p><p>Moscow</p><p>Scopus Author ID: 6505479504; WoS Researcher ID: Q-1385-2015</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9964-5199</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачкасов</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Achkasov</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ачкасов Евгений Евгеньевич – д.м.н., профессор, заведующий кафедрой спортивной медицины и медицинской реабилитации Института клинической медицины им. Н.В. Склифосовского, директор Клиники медицинской реабилитации</p><p> </p><p>ул. Большая Пироговская, д. 2, стр. 4, Москва 119991</p></bio><bio xml:lang="en"><p>Evgeniy E. Achkasov – Dr. Med. Sc., Professor, Chief of Chair of Sports Medicine and Rehabilitation, Sklifosovsky Institute of Clinical Medicine, Director of Clinic for Medical Rehabilitation</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7629-3773</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акарачкова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Akarachkova</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Акарачкова Елена Сергеевна – д.м.н., чл.-корр. Российской академии естественных наук, невролог, президент; заместитель главного врача</p><p>ул. Мусы Джалиля, д. 40, Москва 115573</p><p>ул. Лесная, д. 8, Московская обл., Истринский р-н, с. Павловская Слобода 143581</p></bio><bio xml:lang="en"><p>Elena S. Akarachkova – Dr. Med. Sc., Corresponding Member of RANS, Neurologist, President; Deputy Chief Physician, Rehaline Rehabilitation Centre</p><p>Pavlovskaya Sloboda</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котова Ольга Владимировна – к.м.н., врач-психиатр, психотерапевт, невролог, вице-президент; доцент кафедры психиатрии, психотерапии и психосоматической патологии Медицинского института </p><p>ул. Мусы Джалиля, д. 40, Москва 115573</p><p>ул. Миклухо-Маклая, д. 6, Москва 117198</p></bio><bio xml:lang="en"><p>Olga V. Kotova – MD, PhD, Psychiatrist, Psychotherapist, Neurologist, Vice-President; Associate Professor, Chair of Psychiatry, Psychotherapy and Psychosomatic Pathology, Medical Institute</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-2166-2574</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акавова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Akavova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Акавова Саида Абдулкадыровна – врач-онколог, заведующая Центром амбулаторной поликлинической помощи</p><p>Загородное ш., д. 18А, стр. 7, Москва 117152</p></bio><bio xml:lang="en"><p>Saida A. Akavova – MD, Oncologist, Head of Outpatient Care Center</p><p>Moscow, Russia).</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6619-6179</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галкин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Galkin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галкин Всеволод Николаевич – д.м.н., профессор, главный врач </p><p>Загородное ш., д. 18А, стр. 7, Москва 117152</p></bio><bio xml:lang="en"><p>Vsevolod N. Galkin – Dr. Med. Sc., Professor, Chief Physician</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быковщенко</surname><given-names>Г. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Bykovshchenko</surname><given-names>G. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Быковщенко Георгий Константинович – студент 4-го курса </p><p>ул. Большая Пироговская, д. 2, стр. 4, Москва 119991</p></bio><bio xml:lang="en"><p>Georgy K. Bykovshchenko – 4th Year Student</p><p>Moscow</p></bio><email xlink:type="simple">gbk3004@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5083-6581</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Санджиева</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sandzhieva</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санджиева Лидия Николаевна – к.м.н., врач акушер-гинеколог отделения вспомогательных репродуктивных технологий</p><p>Шоссе Энтузиастов, д. 12, Московская обл., Балашиха 143900</p></bio><bio xml:lang="en"><p>Lidia N. Sandzhieva – MD, PhD, Obstetrician-Gynecologist, Department of Assisted Reproductive Technology</p><p>Balashikha</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0459-0488</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корабельников</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Korabelnikov</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корабельников Даниил Иванович – к.м.н., заведующий кафедрой внутренних болезней с курсами семейной медицины, функциональной диагностики, инфекционных болезней, профессиональных болезней, ректор </p><p>ул. 2-я Брестская, д. 5, стр. 1-1а, Москва 123056</p></bio><bio xml:lang="en"><p>Daniil I. Korabelnikov – MD, PhD, Chief of Chair of Internal Medicine with Courses in Family Medicine, Functional Diagnostics, Infectious and Professional Diseases, Rector</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7738-1858</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блбулян</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Blbulyan</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блбулян Татевик Арменовна – к.м.н., ассистент кафедры акушерства и гинекологии № 2 </p><p>ул. Корюна, д. 2, Ереван 0025</p></bio><bio xml:lang="en"><p>Tatevik A. Blbulyan – MD, PhD, Assistant Professor, Chair of Obstetrics and Gynecology No. 2</p><p>Yerevan</p></bio><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5849-5585</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петренко</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrenko</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петренко Дарья Андреевна – клинический ординатор кафедры клинической фармакологии и пропедевтики внутренних болезней </p><p>ул. Большая Пироговская, д. 2, стр. 4, Москва 119991</p></bio><bio xml:lang="en"><p>Daria A. Petrenko – MD, Clinical Resident, Chair of Clinical Pharmacology and Propaedeutics of Internal Diseases</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8660-7951</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власина</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasina</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Власина Анастасия Юрьевна – к.м.н., врач акушер-гинеколог</p><p>Scopus Author ID: 1016902; WoS Researcher ID: AAF-3130-2020</p><p>ул. Большая Пироговская, д. 2, стр. 4, Москва 119991</p></bio><bio xml:lang="en"><p>Anastasia Yu. Vlasina – MD, PhD, Obstetrician-Gynecologist</p><p>Moscow</p><p>Scopus Author ID: 1016902; WoS Researcher ID: AAF-3130-2020</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет; Институт Превентивной и Социальной Медицины; Автономная некоммерческая организация дополнительного профессионального образования «Московский медико-социальный институт им. Ф.П. Гааза»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sklifosovsky Institute of Clinical Medicine, Sechenov University; Institute for Preventive and Social Medicine; Moscow Haass Medical Social Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Международное общество «Стресс под контролем»; Реабилитационный центр Rehaline</institution><country>Россия</country></aff><aff xml:lang="en"><institution>International Society “Stress Under Control”; Rehaline Rehabilitation Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Международное общество «Стресс под контролем»; Федеральное государственное автономное образовательное учреждение высшего образования «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>International Society “Stress Under Control”; Peoples' Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения г. Москвы «Городская клиническая онкологическая больница № 1 Департамента здравоохранения г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncological Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Московской области «Московский областной перинатальный центр»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Perinatal Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Автономная некоммерческая организация дополнительного профессионального образования &#13;
«Московский медико-социальный институт им. Ф.П. Гааза»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Haass Medical Social Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>Ереванский государственный медицинский университет им. Мхитара Гераци</institution><country>Армения</country></aff><aff xml:lang="en"><institution>Mkhitar Heratsi Yerevan State Medical University</institution><country>Armenia</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2023</year></pub-date><volume>15</volume><issue>3</issue><elocation-id>232–245</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Blinov D.V., Solopova A.G., Achkasov E.E., Akarachkova E.S., Kotova O.V., Akavova S.A., Galkin V.N., Bykovshchenko G.K., Sandzhieva L.N., Korabelnikov D.I., Blbulyan T.A., Petrenko D.A., Vlasina A.Y., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Блинов Д.В., Солопова А.Г., Ачкасов Е.Е., Акарачкова Е.С., Котова О.В., Акавова С.А., Галкин В.Н., Быковщенко Г.К., Санджиева Л.Н., Корабельников Д.И., Блбулян Т.А., Петренко Д.А., Власина А.Ю.</copyright-holder><copyright-holder xml:lang="en">Blinov D.V., Solopova A.G., Achkasov E.E., Akarachkova E.S., Kotova O.V., Akavova S.A., Galkin V.N., Bykovshchenko G.K., Sandzhieva L.N., Korabelnikov D.I., Blbulyan T.A., Petrenko D.A., Vlasina A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.epilepsia.su/jour/article/view/928">https://www.epilepsia.su/jour/article/view/928</self-uri><abstract><p>Background. Radical treatment of malignant neoplasms (MNs) of female reproductive system often has serious consequences. Chronic pain syndrome, distress, anxiety and depression, decreased self-esteem, sexual dysfunction and social maladjustment reduce quality of life (QoL) and require psychotherapeutic support.Objective: to create an algorithm for the provision of comprehensive psychotherapeutic support during rehabilitation following the treatment of reproductive system MNs and to evaluate its effect on QoL indicators in women with neuropsychiatric disorders.Material and methods. The algorithm for the provision of comprehensive psychotherapeutic support included clinical interview, cognitive behavioral therapy, visualization, audio therapy, art therapy, group and individual psychotherapy, family psychotherapy, image therapy. The QoL indicators were determined by questionnaires using the Functional Assessment of Cancer Therapy – General (FACT-G) with nosology-specific extensions (subscales of physical well-being, social/family well-being, emotional wellbeing and functional well-being), Hospital Anxiety and Depression Scale (HADS), Kupperman–Uvarova Modified Menopausal Index (MMI). The follow-up period was 1 year after radical surgical treatment of reproductive system MNs in different localizations. The main group received the algorithm for the provision of comprehensive psychotherapeutic support as part of active medical rehabilitation, the comparison group received basic rehabilitation.Results. The study included 47 women with vulvar cancer (VC): active rehabilitation group (VC-1) – 24 patients and basic rehabilitation group (VC-2) – 23 patients; 61 women with endometrial cancer (EC): active rehabilitation group (EC-1) – 29 patients and basic rehabilitation group (EC-2) – 32 patients; 103 women with cervical cancer (CC): active rehabilitation group (CC-1) – 51 patients and basic rehabilitation group (CC-2) – 52 patients; 62 women with stages I–II ovarian cancer (OC) and low malignant potential tumor (LMPT): active rehabilitation group (LMPT-1) – 29 patients and basic rehabilitation group (LMPT-2) – 33 patients. Differences in physical, social/family and functional well-being (FACT-G) were significant from the 6th month and in emotional well-being – by the end of follow-up. Neurovegetative and psycho-emotional disorders, as assessed by Kupperman–Uvarova MMI, showed significant positive dynamics in women who received the algorithm for the provision of comprehensive psychotherapeutic support, in contrast to the comparison group, where these indicators remained without significant dynamics or worsened by the end of the follow-up period. The HADS scores during psychotherapeutic support decreased to normal values at the 6–12th months of follow-up, while those who received the basic rehabilitation continued to have subclinical anxiety and depression.Conclusion. The developed algorithm for psychotherapeutic support as part of active medical rehabilitation of women who underwent radical treatment for reproductive system MNs (VC, EC, CC, OC, and LMPT) has demonstrated its effectiveness, justifuing its implementation in clinical practice.</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность. Радикальное лечение злокачественных новообразований (ЗНО) женской репродуктивной системы часто приводит к тяжелым последствиям. Хронический болевой синдром, дистресс, тревога и депрессия, снижение самооценки, сексуальная дисфункция и социальная дезадаптация снижают качество жизни (КЖ), обусловливая потребность в психотерапевтической поддержке.Цель: создание алгоритма комплексной психотерапевтической поддержки в период реабилитации после лечения ЗНО репродуктивной системы и оценка его влияния на показатели КЖ женщин с психоневрологическими нарушениями.Материал и методы. В алгоритм комплексной психотерапевтической поддержки включены клиническая беседа, когнитивно-поведенческая психотерапия, визуализация мысленных образов, аудиотерапия, арт-терапия, групповая и индивидуальная психотерапия, семейная психотерапия, имидж-терапия. Показатели КЖ определяли методом анкетирования с использованием Шкалы функциональной оценки терапии рака (англ. Functional Assessment of Cancer Therapy – General, FACT-G) с расширениями в зависимости от нозологии (субшкалы физического состояния, социально-семейных взаимоотношений, эмоционального благополучия и благополучия в повседневной жизни), Госпитальной шкалы тревоги и депрессии (англ. Hospital Anxiety and Depression Scale, HADS), Модифицированного менопаузального индекса (ММИ) Куппермана–Уваровой. Продолжительность наблюдения составила 1 год после радикального хирургического лечения ЗНО репродуктивной системы различной локализации. В основной группе применяли алгоритм комплексной психотерапевтической поддержки в составе активной медицинской реабилитации, в группе сравнения назначали базовую реабилитацию.Результаты. В исследование вошли 47 женщин с раком вульвы (РВ): группа активной реабилитации (РВ-1) – 24 пациентки и группа базовой реабилитации (РВ-2) – 23 пациентки; 61 женщина с раком эндометрия (РЭ): группа активной реабилитации (РЭ-1) – 29 пациенток и группа базовой реабилитации (РЭ-2) – 32 пациентки; 103 женщины с раком шейки матки (РШМ): группа активной реабилитации (РШМ-1) – 51 пациентка и группа базовой реабилитации (РШМ2) – 52 пациентки; 62 женщины с раком яичников (РЯ) I–II стадий и пограничными опухолями яичников (ПОЯ): группа активной реабилитации (ПОЯ-1) – 29 пациенток и группа базовой реабилитации (ПОЯ-2) – 33 пациентки. Различия в показателях физического состояния, социально-семейных взаимоотношений и благополучия в повседневной жизни (FACT-G) становились достоверными с 6-го месяца, эмоционального благополучия – к концу наблюдения. Показатели нейровегетативных и психоэмоциональных нарушений при оценке по ММИ Куппермана–Уваровой демонстрировали достоверную позитивную динамику при применении алгоритма комплексной психотерапевтической поддержки, в отличие от группы сравнения, где данные показатели оставались без существенной динамики или ухудшились к концу периода наблюдения. Показатели по HADS на фоне психотерапевтической поддержки на 6–12-м месяцах наблюдения снижались до нормальных значений, в то время как у получавших базовую реабилитацию продолжала иметь место субклиническая тревога и депрессия.Заключение. Разработанный алгоритм психотерапевтической поддержки в составе медицинской активной реабилитации женщин после радикального лечения ЗНО репродуктивной системы (РВ, РЭ, РШМ, РЯ, ПОЯ) продемонстрировал свою эффективность, что дает основания рекомендовать его к внедрению в клиническую практику. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>Злокачественные новообразования</kwd><kwd>ЗНО</kwd><kwd>репродуктивная система</kwd><kwd>хронический болевой синдром</kwd><kwd>ХБС</kwd><kwd>стресс</kwd><kwd>тревога</kwd><kwd>депрессия</kwd><kwd>социальная дезадаптация</kwd><kwd>психотерапия</kwd><kwd>реабилитация</kwd><kwd>качество жизни</kwd><kwd>КЖ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Malignant neoplasms</kwd><kwd>MNs</kwd><kwd>reproductive system</kwd><kwd>chronic pain syndrome</kwd><kwd>CPS</kwd><kwd>stress</kwd><kwd>anxiety</kwd><kwd>depression</kwd><kwd>social maladaptation</kwd><kwd>psychotherapy</kwd><kwd>rehabilitation</kwd><kwd>quality of life</kwd><kwd>QoL</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Franasiak J.M., Scott R.T. 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