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Vol 8, No 3 (2016) THE ROLE OF THE THERAPEUTIC DRUG MONITORING WHEN USING ANTIEPILEPTIC DRUGS Abstract  similar documents
A. V. Yakunina, I. E. Poverennova
"... Objective. To define therapeutic drug monitoring (TDM) role when using drugs of valproic acid ..."
 
Vol 9, No 1 (2017) THERAPEUTIC DRUG MONITORING OF ANTICONVULSANTS IN CHILDREN IN CLINICAL PRACTICE Abstract  similar documents
M. V. Leonova, M. A. Ivzhits, I. F. Tischenkova, L. L. Shteinberg
"... features of valproic acid pharmacokinetics  in newborns  and children are associated  with specific TDM ..."
 
Vol 5, No 4 (2013) THERAPEUTIC DRUG MONITORING OF LAMOTRIGINE: DEVELOPMENT OF PHARMACOKINETIC APPROACHES AIMING AT THE INDIVIDUAL-BASED ANTICONVULSIVE PHARMACOTHERAPY Abstract  similar documents
D. A. Abaimov, A. K. Sariev, M. V. Tankevich, E. Yu. Styrova, V. V. Schvedkov, T. Yu. Noskova, R. D. Seifulla
"... полувыведения ламотриджина. Так, вальпроевая кислота, ингибируя глюкурониро- вание ламотриджина, увеличивает ..."
 
Vol 4, No 2 (2012) NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING Abstract  similar documents
Z. А. Suslina, А. K. Sariev, D. А. Аbaimov, T. YU. Noskova, R. D. Sejfulla, V. V. Shvedkov, D. I. Prokhorov, M. V. Shiryaeva, L. А. Mota
"... У 47 больных с фокальной эпилепсией проводился терапевтический лекарственный мониторинг (ТЛМ ..."
 
Vol 5, No 2 (2013) MODERN TECHNOLOGIES IN THERAPEUTIC DRUG MONITORING (REVIEW) Abstract  similar documents
D. A. Abaimov, A. K. Sariev, T. Yu. Noskova, V. V. Shvedkov, M. V. Shiryaeva, E. Yu. Styrova, D. I. Prokhorov, R. D. Seyfulla
"... therapy in modern medicine. In the article various aspects of the therapeutic drug monitoring (TDM ..."
 
Vol 6, No 2 (2014) COMPARATIVE EVALUATION OF THE EFFICACY AND SAFETY OF VALPROIC ACID DERIVATIVES Abstract  similar documents
O. L. Badalyan, S. G. Burd, A. A. Savenkov, G. G. Avakyan, E. V. Yutskova, G. N. Avakyan
"... Abstract: this article discusses the comparative efficacy and safety of valproic acid derivatives ..."
 
Vol 5, No 3 (2013) THERAPEUTIC DRUG MONITORING OF ANTICONVULSANTS IN CLINICAL PRACTICS Abstract  similar documents
Yu. B. Belousov, M. V. Leonova, L. L. Shteinberg, I. F. Tischenkova, A. V. Sokolov
"... Abstract: his paper presents the results of therapeutic drug monitoring (TDM) of anticonvulsants ..."
 
Vol 10, No 2 (2018) Chromatography-tandem MASS spectrometry (HPLC-MS/MS) for the detection of valproic acid and its metabolites in blood plasma Abstract  similar documents
A. S. Malygin, N. S. Popov, M. A. Demidova, M. N. Kudrayshova
"... Aim: to adapt the HPLC-MS/MS technique to determining valproic acid and its metabolites in blood ..."
 
Vol 1, No 1 (2009) TREATMENT OF EPILEPSY WITH PROLONGED VALPROIC ACID FORMULATIONS IN OUT-PATIENT SETTINGS Abstract  similar documents
G. N. Avakyan, О. М. Oleinikova, Е. А. Khromykh, О. L. Badalyan, Yu. V. Lagutin
"... either as start-up therapy or following a forced switch to these drugs from the original valproic acid ..."
 
Vol 6, No 4 (2014) RESULTS OF THERAPEUTIC DRUG MONITORING COMBINATION THERAPY OF ANTICONVULSANTS IN CLINICAL PRACTICS Abstract  similar documents
M. V. Leonova, Yu. B. Belousov, I. F. Tischenkova, L. L. Shteinberg, A. V. Sokolov
"... Abstract: this paper presents the results of therapeutic drug monitoring (TDM) of anticonvulsants ..."
 
Vol 9, No 2 (2017) 4-BENZOYLPYRIDINE OXIME DERIVATIVE (GIZH-298) VERSUS VALPROIC ACID: THE ANTICONVULSANT POTENTIAL EFFECT IN A MODEL OF EPILEPSY IN RATS WITH COBALT-INDUCED LESIONS Abstract  similar documents
I. O. Gaydukov, S. A. Litvinova, T. A. Voronina, L. N. Nerobkova, L. A. Zhmurenko, G. V. Mokrov, G. G. Avakyan, I. S. Kutepova
"... GIZH-298 (4-benzoylpyridine oxime derivative) versus valproic acid (VPA) in a model of epilepsy in rats ..."
 
Vol 9, No 3 (2017) USE OF VALPROIC ACID IN WOMEN WITH EPILEPSY DURING PREGNANCY Abstract  similar documents
A. V. Yakunina, I. E. Poverennova, V. A. Kalinin, S. A. Nenasheva
"... Objective: to evaluate the use of valproic acid in treatment of epilepsy during pregnancy ..."
 
Vol 5, No 4 (2013) EXPERIENCE REPLACEMENT DRUGS OF VALPROIC ACID IN CHILDREN OUTPATIENT CLINIC Abstract  similar documents
I. O. Schederkina, N. N. Zavadenko, I. E. Koltunov
"... drug valproic acid. Such changes in anticonvulsant therapy in patients quarter led to a deterioration ..."
 
Vol 8, No 4 (2016) NONCONVULSIVE STATUS EPILEPTICUS IN PATIENTS WITH LIMBIC ENCEPHALITIS Abstract  similar documents
M. A. Sherman, I. V. Ardashev, I. V. Ponomareva, H. Sherman
"... of glucocorticoid pulse-therapy, complimented by long-term regiment of valproic acid, is shown as a successful ..."
 
Vol 3, No 1 (2011) Possible pathogenetic mechanisms of failure epilepsy treatment with carbamazepine Abstract  similar documents
K. V. Krikova, S. G. Burd
 
Vol 3, No 2 (2011) POSSIBILITIES OF APPLICATION THE PROLONGED FORM VALPROIC ACID AND ANTIOXIDANT IN SECONDARYGENERALIZED SEIZURES (clinical and experimental investigation) Abstract  similar documents
G. G. Avakyan, L. N. Nerobkova, O. M. Oleynikova, T. A. Voronina, G. N. Avakyan, E. I. Gusev
"... Possibilities of application the prolonged form valproic acid and antioxidant in secondary ..."
 
Vol 6, No 4 (2014) THE BASIC REGULATOR OF THE CIRCADIAN SYSTEM IN EPILEPSY Abstract  similar documents
G. N. Avakyan, O. M. Oleinikova, E. N. Kareva, M. A. Bogomazova
"... with valproic acid compared with carbamazepine. ..."
 
Vol 8, No 1 (2016) EPILEPSY AT ADULTS: GENDER COMORBIDE DISORDERS, APPLICATION OF VALPROATES Abstract  similar documents
P. N. Vlasov
"... sphere. The valproic acis remains the substance, referred to the first choice group in the treatment ..."
 
Vol 6, No 2 (2014) TERATOGENESIS OF ANTIEPILEPTIC DRUGS: REVIEW AND CLINICAL CASES Abstract  similar documents
D. V. Dmitrenko, N. A. Shnayder
"... . The current approaches to refining birth defects in children whose mothers took the valproic acid drugs during ..."
 
Vol 11, No 2 (2019) Restrictions on the use of valproate in female patients of reproductive age: the updated recommendations based on recent clinical data Abstract  similar documents
G. N. Avakyan, D. V. Blinov, G. G. Avakyan, E. S. Akarachkova, S. G. Burd, P. N. Vlasov, K. V. Voronkova, V. I. Guzeva, I. A. Zhidkova, E. A. Katunina, D. I. Korabelnikov, A. V. Lebedeva, L. V. Lipatova, E. A. Morozova, O. M. Oleinikova, I. G. Rudakova
"... For more than half a century, valproic acid (VA) has been a first-line drug to control seizures ..."
 
Vol 9, No 2 (2017) TRANSFORMATION OF THE EPILEPTIC SYSTEM. CURRENT STATUS OF THE PROBLEM AND POSSIBLE WAYS TO SOLVE IT Abstract  similar documents
G. N. Avakyan, G. G. Avakyan
"... We have conducted an experiment with valproic acid drugs (used as an example), where we have ..."
 
Vol 7, No 2 (2015) CLINICAL CASE OF PREGNANT PATIENT WITH TEMPORAL EPILEPSY AND MYOCLONIC EPILEPTIC SEIZURES Abstract  similar documents
V. O. Generalov, T. R. Sadykov, N. I. Klimenchenko, A. M. Yugay, Yu. V. Kazakova, E. V. Tsalagova, O. V. Shetikova
"... , Valproic acid in therapeutic doses without any result. On video-EEG monitoring focal epileptic activity ..."
 
Vol 8, No 2 (2016) PROTECTION OF BRAIN MITOCHONDRIA AGAINST MICRO STROKE-INDUCED INJURY: A STUDY OF ETHYLMETHYLHYDROXYPYRIDINE SUCCINATE IN EXPERIMENTAL MODEL USING TWO PHOTON LASER FLUORESCENT MICROSCOPY Abstract  similar documents
R. A. Afzalov, Yu. O. Kolikova, E. G. Pryazhnikov, D. V. Toptunov, L. S. Khirug
"... .p. at 30 min after the stroke onset. A period of observation was 48 h. Brain images were obtained by two ..."
 
Vol 4, No 4 (2012) EXPERIENCE OF TREATMENT WITH GENERIC LAMOTRIDJIN IN DIFFERENT FORMS OF EPILEPSY (The results of focus observation in out-patient clinics network of Moscow city public healthcare services) Abstract  similar documents
O. L. Badalyan, M. A. Bogomazova, I. I. Zhuravleva, A. M. Ismailov, . ., E. G. Komelkova, L. N. Lesinker, Yu. I. Logvinov, O. V. Otcheskaya, S. V. Petrov, Yu. V. Solomatin, A. M. Teplysheva, T. N. Udovuchenko, A. E. Khromykh, A. S. Chukanova, A. V. Lebedeva, S. G. Burd, A. N. Boiko
"... . Patients sample included 20 patients, receiving valproic acid in various dosages and 12 patients, receiving ..."
 
Vol 11, No 1 (2019) Efficacy of levetiracetam monotherapy in epilepsy associated with benign epileptiform discharges of childhood Abstract  similar documents
N. A. Borovkova, A. G. Malov
"... received antiepileptic treatment with valproic acid, and 17 children received levetiracetam ..."
 
Vol 9, No 4 (2017) NON-INVASIVE ASSESSMENT OF ANTI-SEIZURE DRUGS AND THEIR ABILITY TO PREVENT EPILEPTIFORM CHANGES Abstract  similar documents
R. G. Paronikyan, R. Sh. Sarkisyan, M. N. Avagyan, M. S. Grigoryan, A. D. Paronikyan
"... , a pronounced peak in the frequency range of 0.3 osc/min is formed in the spectral distribution of inter-peak BB ..."
 
Vol 10, No 2 (2018) Hyperandrogenism as a side effect of anticonvulsants Abstract  similar documents
E. V. Tsallagova, V. O. Generalov, T. R. Sadykov
"... of dihydrotestosterone were monitored in 278 women taking various antiepileptic drugs (valproic  acid, carbamazepine ..."
 
Vol 2, No 2 (2010) PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY Abstract  similar documents
M. Ya. Kissin, I. I. Bondarenko
"... ,4%, 10 жен- щин – 47,6%) Средняя частота припадков в месяц 2,31±1,36 (min – 1, max – 5) 2,16±1 ..."
 
Vol 2, No 2 (2010) PREGABALIN AND ALPRAZOLAM IN TREATMENT OF GENERALIZED ANXIETY DISORDER IN PATIENTS WITH PARTIAL EPILEPSY Abstract  similar documents
M. Ya. Kissin, I. I. Bondarenko
"... ,4%, 10 жен- щин – 47,6%) Средняя частота припадков в месяц 2,31±1,36 (min – 1, max – 5) 2,16±1 ..."
 
Vol 7, No 1 (2015) ALPERS-HUTTENLOCHER SYNDROME Abstract  similar documents
T. T. Batysheva, V. M. Trepilets, L. Ya. Akhadova, G. S. Golosnaya
"... . Valproic acid causes toxic fatal hepatitis developing within several months and leading to the loss ..."
 
Vol 2, No 3 (2010) TOPICAL ISSUES OF EPILEPTOLOGY – STIGMATIZATION, QUALITY OF LIFE AND REHABILITATION OF PATIENTS Abstract  similar documents
V. A. Mikhailov
"... as carbamazepine, valproic acid, lamotrigine and topiramate allows control of quality of life and stigmatization ..."
 
Vol 8, No 1 (2016) EPILEPSY IN INBORN ERRORS OF METABOLISM Abstract  similar documents
E. D. Belousova
"... to inherited metabolic epilepsies. Probably it’s better to avoid the treatment with valproic acid in clinical ..."
 
Vol 6, No 4 (2014) THE ROLE OF HEREDITARY DISORDERS OF METABOLISM of FOLIC ACID IN THE DEVELOPMENT OF CONGENITAL DEFECT FETUS IN WOMEN WITH EPILEPSY AND RECEIVING ANTIEPILEPTIC DRUGS Abstract  similar documents
D. V. Dmitrenko, N. A. Shnayder, Y. B. Govorina, A. V. Muravievа, K. A. Gazenkampf
"... вальпроевой кислоты (ВК) в крови (в мкг/мл). ТЛМ проводился в лаборатории «Инвитро» (Красноярск ..."
 
Vol 10, No 2 (2018) The spectrum and efficacy of antiepileptic drugs in patients with infantile spasms in Russia Abstract  similar documents
T. G. Okhapkina, I. V. Shuljakova, E. S. Ilina, G. V. Kalmykova, M. V. Prytkina, E. D. Belousova
"... for the treatment with hormonal therapy. Results. Valproic acid was the most commonly prescribed antiepileptic drug ..."
 
Vol 9, No 1 (2017) ADVERSE EFFECTS OF ANTIEPILEPTIC DRUGS Abstract  similar documents
I. Yu. Kovaleva
"... . Появление акне и гипертрихоза связывают с воз- действием вальпроевой кислоты (ВПК) на уровень андрогенов у ..."
 
Vol 7, No 1 (2015) SEVERE EPILEPTIC ENCEPHALOPATHY OF EARLY CHILDHOOD DUE TO SCN2A MUTATION Abstract  similar documents
I. S. Bachtin, E. D. Belousova, P. A. Shatalov, S. O. Ayvazyan
"... antiepileptic drugs including valproic acid, topiramate, lamotrigine, ethosuximide and tetracoside. At age ..."
 
Vol 2, No 3 (2010) THE EFFICACY OF ANTI-EPILEPTIC TREATMENT IN ADULTS BEFORE AND AFTER ITS CORRECTION BY EPILEPTOLOGIST Abstract  similar documents
P. N. Vlasov, N. V. Orekhova
"... . The prolonged forms of valproic acid started to be used 1.75-fold more often (from 20.6% to 36 ..."
 
Vol 11, No 1 (2019) CLINICAL AND NEUROLOGICAL MANIFESTATIONS OF DRUG-RESISTANT EPILEPSY AND OPTIMIZATION OF PATIENT TREATMENT Abstract  similar documents
Yo. N. Madjidova, A. A. Solikhzoda, Kh. N. Maksudova
"... . For the anticonvulsant therapy, both groups received the combinations of valproic acid (30 mg/kg at two daily doses ..."
 
Vol 2, No 3 (2010) ТЕРАПЕВТИЧЕСКИЙ ЛЕКАРСТВЕННЫЙ МОНИТОРИНГ АНТИКОНВУЛЬСАНТОВ У ДЕТЕЙ Abstract  similar documents
"... . Для карбамазепина и вальпроевой кислоты интерпретация результатов ТЛМ осложнена в связи с наличием ..."
 
Vol 9, No 1 (2017) Editorial of Editor-in-Chief prof. G.N. Avakyan Abstract  similar documents
G. N. Avakyan
"... фармакокинетики вальпроевой кислоты авторы обосновывают высокую значимость применения ТЛМ у новорожденных и ..."
 
Vol 1, No 1 (2009) VISUAL EVOKED POTENTIALS OF SICK INFANTS WITH EPILEPSY Abstract  similar documents
V. P. Zykov, I. M. Mosin, D. L. Safronov, E. B. Izumova, I. L. Stepanishev, O. A. Voronenko
"... -20 0 20 40 60 80 100 min ; -7 min ; 22 min ; 68 max ; 27 max ; 62 max ; 88 11,3 + -13 ..."
 
Vol 4, No 3 (2012) WAYS OF IMPROVEMENT OF PHARMACOTHERAPY OF EPILEPSY AT CHILDREN: FOCUS ON SPECIFIC FEATURES OF BIOTRANSFORMATION MEDICINES Abstract  similar documents
B. I. Kantemirova, A. K. Starodubtsev, D. A. Sychev, V. V. Belopasov, Zh. M. Tsotsonava, V. I. Griganov
"... детей раннего возраста, являются произво- дные вальпроевой кислоты и карбамазепина. Вальпроевая кислота ..."
 
Vol 2, No 1 (2010) Reproductive disorders in male patients with epilepsy Abstract  similar documents
G. N. Avakyan, O. L. Badalyan, E. V. Krikova, A. S. Chukanova, S. G. Burd
"... et al., 2004; Röste LS et al., 2003). Вальпроевая кислота не является индуктором ферментов печени ..."
 
Vol 4, No 2 (2012) NONCONVULSIVE SEIZURES AND NONCONVULSIVE EPILEPTIC STATUS. NEW THERAPEUTIC OPPORTUNITIES Abstract  similar documents
A. V. Lebedeva, V. E. Khomutov, . ., D. V. Guz
"... действия вальпрое- вой кислоты позволило выделить ряд форм эпилепсии, при которых препараты вальпроевой ..."
 
Vol 7 (2015): Special issue ОТ ФЕНОБАРБИТАЛА К ЭСЛИКАРБАЗЕПИНУ Abstract  similar documents
"... вальпро- евой кислоты, которая уже много лет применялась как технический растворитель. Так начался второй ..."
 
Vol 9, No 2 (2017) Editorial of Editor-in-Chief prof. G.N. Avakyan Abstract  similar documents
G. N. Avakyan
"... - дования противосудорожного эффекта нового оригинального соединения ГИЖ-298 с вальпрое- вой кислотой (ВК ..."
 
Vol 7, No 1 (2015) ЗАКЛЮЧЕНИЕ СОВЕТА ЭКСПЕРТОВ ПО ЭПИЛЕПТОЛОГИИ. (17 ИЮНЯ 2014 Г.). «ПСЕВДОФАРМАКОРЕЗИСТЕНТНОСТЬ ЭПИЛЕПСИИ – СОВРЕМЕННОЕ СОСТОЯНИЕ, ПРОБЛЕМЫ И ПУТИ РЕШЕНИЯ» Abstract  similar documents
, , , , , , , , , ,
"... .ч. и наиболее назначаемыми в РФ базисными препаратами: карбамазепином и вальпрое- вой кислотой ..."
 
Vol 1, No 1 (2009) PREGNANCY IN EPILEPSY: AN EVIDENCE-BASED MEDICINE APPROACH Abstract  similar documents
P. N. Vlasov
"... : эпилепсия, беременность, АЭП. Сокращения: АЭП – антиэпилептические пре- параты, ВК – вальпроевая кислота ..."
 
Vol 2, No 2 (2010) DYSEMBRYOGENETIC STIGMATA AND PHYSICAL DEVELOPMENT IN CHILDREN BORN TO EPILEPTIC MOTHERS Abstract  similar documents
A. B. Kozhokaru, V. A. Karlov, I. A. Zhidkova, A. V. Serkina
"... нейроповеденческие эффекты были най- дены при использовании таких противоэпилептиче- ских препаратов, как вальпроевая ..."
 
Vol 6, No 3 (2014) IMMUNE DISTURBANCES IN PATIENTS WITH EPILEPSY AND OPPORTUNITY OF IMMUNOMODULATION BY RECOMBINANT HUMAN IL-2 Abstract  similar documents
L. V. Lipatova, N. B. Serebryanya, N. A. Sivakova, A. V. Vasilenko, T. V. Kapustina
"... [32]. Цитокины в плазме крови Здоровые доноры (n=13) Me (min-max) Больные эпилепсией (n=34) Me (min ..."
 
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