Preview

Epilepsy and paroxysmal conditions

Advanced search

ЭФФЕКТИВНОСТЬ И ПЕРЕНОСИМОСТЬ ПЕРАМПАНЕЛА У ПОДРОСТКОВ И ВЗРОСЛЫХ С РЕЗИСТЕНТНОЙ ФОКАЛЬНОЙ ЭПИЛЕПСИЕЙ. ОБЗОР ДАННЫХ МЕЖДУНАРОДНЫХ ИССЛЕДОВАНИЙ

Full Text:

Abstract

.

About the Author

Е. Белоусова
Научно-исследовательский клинический институт педиатрии имени академика Ю.Е. Вельтищева Российского национального исследовательского медицинского университета имени Н.И. Пирогова, Москва
Russian Federation


References

1. Kwan P., Brodie M.J. Effectiveness of first antiepileptic drug. Epilepsia. 2001; 42 (10): 1255-60.

2. Schiller Y., Najjar Y. Quantifying the response to antiepileptic drugs: effect of past treatment history. Neurology. 2008; 70 (1): 54-65.

3. Rogawski M.A. Revisiting AMPA receptors as an antiepileptic drug target. Epilepsy Currents. 2011; 11: 56-63.

4. Hanada T. et al. Perampanel: A novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy. Epilepsia. 2011; 52: 1331-40.

5. French J.A. et al. Adjunctive perampanel for refractory partial-onset seizures: randomized phase III study 304. Neurology. 2012; 79: 589-96.

6. French J.A. et al. Evaluation of adjunctive perampanel in patients with refractory partial- onset seizures: Results of randomized global phase III study 305. Epilepsia. 2013; 54: 117-25.

7. Krauss G.L. et al. Randomized phase III study 306: adjunctive perampanel for partial onset seizures. Neurology. 2012; 78: 1408-15.

8. Steinhoff B.J. et al. Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: A pooled analysis of three phase III studies. Epilepsia. 2013; 54 (8): 1481-9.

9. Krauss G.L. et al. Perampanel, a selective, noncompetitive a-amino-3-hydroxy-5-methyl-4-isooxazolepropionic acid receptor antagonist, as adjunctive therapy for refractory partial-onset seizures: Interim results from phase III, extension study 307. Epilepsia. 2013; 54: 126.


For citation:


. . Epilepsy and paroxysmal conditions. 2014;6(5):6-9. (In Russ.)

Views: 66


ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)