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Epilepsy syndromes: the 2022 ILAE definition and classification

https://doi.org/10.17749/2077-8333/epi.par.con.2022.123

Abstract

Until recently, no classification of epileptic syndromes officially approved by the International League Against Epilepsy (ILAE) was available. In 2022, owing to many year-persistent efforts made by experts and the public community, the studies providing the definition and classification of epileptic syndromes were published. ILAE has approved the following definition of the epileptic syndrome: “a characteristic cluster of clinical and EEG features, often supported by specific etiological findings (structural, genetic, metabolic, immune, and infectious)”. The classification of epileptic syndromes is proposed according to the age principle: onset in neonates and infants, onset in childhood, onset at a variable age. Separately, the syndromes of idiopathic generalized epilepsy were presented. Clinical data for each epileptic syndrome are presented in a single pattern: epidemiology, clinical context, natural history, type(s) of seizures, electroencephalography, neuroimaging findings, genetic findings, other laboratory findings (when informative), differential diagnosis. The criteria for diagnosis, including mandatory criteria, warning signs and exclusion criteria, are given. This classification should be a starting point for further improvement in the organizing work of practitioners who deal with epilepsy.

About the Author

D. V. Blinov
Institute for Preventive and Social Medicine; Lapino Clinical Hospital, Medical Group “Mother and Child”
Russian Federation

Dmitry V. Blinov – MD, PhD, MBA, Head of Medical and Scientific Affairs; Neurologist

WoS ResearcherID: J-4946-2017;

Scopus Author ID: 7003589812;

RSCI SPIN-code: 6317-98334/10

Sadovaya-Triumfalnaya Str., Moscow 127006

111 1st Uspenskoye Hwy, Moscow Region, Odintsovo District, Lapino 143081



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Supplementary files

1. Приложение A1. Эпилептические синдромы с началом в неонатальном периоде и младенчестве
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2. Приложение А2. Диагностические критерии эпилептических синдромов с началом в неонатальном периоде и младенчестве
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3. Приложение В1. Эпилептические синдромы с началом в детском возрасте
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4. Приложение В2. Диагностические критерии эпилептических синдромов с началом в детском возрасте
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5. Приложение В3. Эпилептические синдромы с началом в детском возрасте: сравнение названий
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6. Приложение С1. Эпилептические синдромы с началом в разном возрасте
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7. Приложение С2. Диагностические критерии эпилептических синдромов с началом в разном возрасте
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8. Приложение С3. Отличительные особенности связанной со сном гипермоторной (гиперкинетической) эпилепсии, семейной мезиальной височной эпилепсии, семейной фокальной эпилепсии с вариабельными очагами и эпилепсии со слуховыми приступами
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9. Приложение D1. Синдромы идиопатической генерализованной эпилепсии
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10. Приложение D2. Диагностические критерии синдромов идиопатической генерализованной эпилепсии
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11. Приложение D3. Отличительные особенности детской абсансной эпилепсии, юношеской абсансной эпилепсии, юношеской миоклонической эпилепсии и эпилепсии с изолированными генерализованными тонико-клоническими приступами
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For citations:


Blinov D.V. Epilepsy syndromes: the 2022 ILAE definition and classification. Epilepsy and paroxysmal conditions. 2022;14(2):101-182. (In Russ.) https://doi.org/10.17749/2077-8333/epi.par.con.2022.123

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ISSN 2311-4088 (Online)