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Epilepsy and paroxysmal conditions

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EPILEPSY IN CHILDREN WITH STROKE

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Abstract

The frequency of detection of stroke in children has increased over the last 25 years (from 1.3 to 13/100 000). The children identified more than 100 risk factors for stroke, but more than a third of cases the cause is not identified. We have analyzed the incidence of epilepsy in children with stroke and risk factors to evaluate the possibility of occurrence of epileptic seizures. It handled 280 case histories of children who had a stroke in the period from 2013 to August 2015 (excluding children with perinatal stroke and bleeding with severe brain injuries) treated at the Morozov Children'sClinicalHospital. All children held in the dynamics of EEG, psychological testing, repeat MRI. The diagnosis of epilepsy had 24 children (8.6%) of the treated patient records. Ischemic stroke was diagnosed in 62%, hemorrhagic – 38%. In HS, prevailed children aged up to 3 years, with ischemic from 6 to 14 years. The most common attacks made their debut from 12 to 24 months after a stroke, some earlier occurrence of attacks observed in hemorrhagic stroke, from 1 month to 12 months (77%). Only 3/24 (12.5%) children seizures were observed in the acute phase stroke. In 71% was a combination of several types of attacks. Two of the children diagnosed with idiopathic forms epilepsy – childhood absence and juvenile myoclonic. Evaluation of the outcome of stroke scale PSOM-SNE and pathopsychological evaluation by the Achenbach revealed more severe neuropsychological problems in children with stroke with epileptic seizures than those without epilepsy. 

About the Authors

I. O. Shchederkina
Morozov Children’s Clinical Hospital, Moscow; Pirogov Russian National Research Medical University, Moscow
Russian Federation

Shсhederkina Inna Olegovna – PhD, neurologist-epileptologist, Morozov Children’s Clinical Hospital, docent, Neurology, Neurosurgery and Medical Genetics Depertment, Pirogov Russian National Research Medical University.

Address: 4 Dobrininsky per., 1/9, Moscow, Russia, 119037.



N. N. Zavadenko
Morozov Children’s Clinical Hospital, Moscow; Pirogov Russian National Research Medical University, Moscow
Russian Federation

Zavadenko Nikolaj Nikolaevich – MD, neurologist, Professor, Head of Department of Neurology, Neurosurgery and Medical Genetics, Pirogov Russian National Research Medical University.

Address: ul. Ostrovityanova, 1, Moscow, Russia, 117997.



I. E. Koltunov
Morozov Children’s Clinical Hospital, Moscow
Russian Federation

Koltunov Igor EfimovichMD, Professor, Honored Doctor of Russia, Head of Morozov Children’s Clinical Hospital.

Address: 4 Dobrininsky per., 1/9, Moscow, Russia, 119037.



References

1. Pediatric Neurology. Clinical guidelines. Ed. V.I. Guzeva [Detskaya nevrologiya. Klinicheskie rekomendatsii. Pod red. V.I. Guzevoi (In Russian)]. Moscow. 2014; 328 s.

2. Zykov V.P., Shiretorova D.Ch., Chuchin M.Yu., Komarova I.B., Stepanishchev I.L., Cherkasov V.G. Diagnosis and treatment of stroke in children. Tutorial. [Diagnostika i lechenie insul’ta u detei. Uchebnoe posobie (In Russian)]. Moscow. 2006; 64 s.

3. Komarova I.B., Zykov V.P. Zh. nevrologii i psikhiatrii im. S.S. Korsakova. 2013; 5: 10-15.

4. Christine K. Fox, Hannah C. Glass. Acute seizures predict epilepsy after childhood stroke. Ann Neurol. 2013; 74 (2): 249-256.

5. De Schryver E.L., Kappelle L.J., JennekensSchinkel A. et al. Prognosis of ischemic stroke in childhood: a long-term follow-up study. Dev. Med. Child. Neurol. 2000; 42 (5): 313-18.

6. Emanuelson I., Uvebrant P. Occurrence of epilepsy during the first 10 years after traumatic brain injury acquired in children up to the age of 18 years in the South western Swedish population-based series. Brain injury. 2009; 23 (7): 612-3.

7. Hills N.K., Johnston S.C., Sidney et al. Recent trauma and acute infection as risk factor for children arterial ischemic stroke. Ann Neurol. 2012; 72 (6): 850-8.

8. Jennett B. Trauma as a cause of epilepsy in childhood. Developmental medicine and child neurology. 1973; 56-62.

9. Lanthier S., Carmant L., David M. et al. Stroke in children: the coexistence of multiple risk factors predicts poor outcome. Neurology. 2000; 54: 371-378.

10. Singh R.K., Zecavati N., Singh J. et al. Seizures in acute childhood stroke. J. Pediatr. 2000; 160; 291-96.

11. Yang J.S., Park Y.D., Hartlage P.L. Seizures associated with stroke in childhood. Pediatr. Neurol. 1995; 12: 136-138.


Review

For citations:


Shchederkina I.O., Zavadenko N.N., Koltunov I.E. EPILEPSY IN CHILDREN WITH STROKE. Epilepsy and paroxysmal conditions. 2015;7(4):66-71. (In Russ.)

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)