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EXPERIENCE OF TREATMENT OF DIFFERENT FORMS OF EPILEPSY WITH GENERIC TOPIRAMATE (The results of focus observation in out-patientclinics network of Moscow city public healthcare services)

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Abstract

Current work is dedicated to analysis of treatment with generic topiramate in mono- as well as in polytherapy in patients with different forms of epilepsy. Forclinical assessmentsHospital Anxiety and Depression Scale (HADS), quality of life questionnaire for patients with epilepsy (QOLIE-10) and efficacy primary assessment based on decrease in frequency of seizures and adverse events before and after switching to generic topiramate were used. As a result of focus investigation switch to Topsaver was associated with maintenance of stable therapeutic effect in more, than 80% of cases. No negative dynamics in changes of HADS and QOLIE-10 points were observed.

About the Authors

O. L. Badalyan
City polyclinics, Moscow
Russian Federation


M. A. Bogomazova
City polyclinics, Moscow
Russian Federation


I. I. Zhuravleva
City polyclinics, Moscow
Russian Federation


A. M. Ismailov
City polyclinics, Moscow
Russian Federation


E. G. Komelkova
City polyclinics, Moscow
Russian Federation


L. N. Lesinker
City polyclinics, Moscow
Russian Federation


Yu. I. Logvinov
City polyclinics, Moscow
Russian Federation


O. V. Otcheskaya
City polyclinics, Moscow
Russian Federation


S. V. Petrov
City polyclinics, Moscow
Russian Federation


Yu. V. Solomatin
City polyclinics, Moscow
Russian Federation


A. М. Teplysheva
City polyclinics, Moscow
Russian Federation


T. N. Udovuchenko
City polyclinics, Moscow
Russian Federation


E. A. Khromykh
City polyclinics, Moscow
Russian Federation


A. S. Chukanova
City polyclinics, Moscow
Russian Federation


A. V. Lebedeva
City polyclinics, Moscow
Russian Federation


S. G. Burd
GBOU VPO RNIMU named after N.I. Pirogov, Moscow
Russian Federation


A. N. Boiko
GBOU VPO RNIMU named after N.I. Pirogov, Moscow
Russian Federation


А. Бойко
ГБОУ ВПО РНИМУ им. Н.И. Пирогова, Москва
Russian Federation


References

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For citation:


Badalyan O.L., Bogomazova M.A., Zhuravleva I.I., Ismailov A.M., Komelkova E.G., Lesinker L.N., Logvinov Y.I., Otcheskaya O.V., Petrov S.V., Solomatin Y.V., Teplysheva A.М., Udovuchenko T.N., Khromykh E.A., Chukanova A.S., Lebedeva A.V., Burd S.G., Boiko A.N., . EXPERIENCE OF TREATMENT OF DIFFERENT FORMS OF EPILEPSY WITH GENERIC TOPIRAMATE (The results of focus observation in out-patientclinics network of Moscow city public healthcare services). Epilepsy and paroxysmal conditions. 2012;4(4):6-10. (In Russ.)

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)