BRAIN BLOOD FLOW EXAMINATION WITH HIGH-FLOOR MRI-PERFUSION DURING THE ATTACK OF MIGRAINE WITHOUT AURA
Abstract
The main goal of our study was to gain knowledge on blood supply changes during an attack in patients with migraine without aura using contrast-enhanced perfusion-weighted MRI (PWI). Standard MRI, and PWI were performed twice: during an attack (in all three cases) and in between attacks (in two cases). Three females with long history of migraine without aura were observed. Cerebral blood volume (CBV), mean transit time of the contrast bolus (MTT), and cerebral blood flow (CBF) were calculated using Functool package. All three cases produced similar local MR perfusion changes that included reduced CBV and decreased CBF without any change in MTT. Cerebral blood supply decrease observed during migraine attack is reversible and absent during headache-free interval. Transient perfusion abnormalities occurring during recurrent attacks and confirmed by PWI may serve as one of the mechanisms causing the small subcortical white matter lesions.
About the Authors
M. I. Koreshkina
Center of treatment of headache. «Scandinavia» clinic (ООО «AVA-PETER»), Saint-Petersburg
Russian Federation
Russian Federation
A. D. Khalikov
ООО «International clinic MEDEM», STbSMA n.a. I.I. Mechnikov, Saint-Petersburg
Russian Federation
Russian Federation
Yu. V. Nazinkina
Institute of Human Brain Russian Academy of Science, Saint-Petersburg
Russian Federation
Russian Federation
V. V. Osipova
Scientific Investigational Center of First MSMU n.a. I.M. Sechenov; Russian Society of Headache Investigation, Moscow
Russian Federation
Russian Federation
A. V. Amelin
Saint-Petersburg State Medical University n.a. I.P. Pavlov
Russian Federation
Russian Federation
E. A. Kosmacheva
International Medical Center «Sogaz», Saint-Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Koreshkina M.I., Khalikov A.D., Nazinkina Yu.V., Osipova V.V., Amelin A.V., Kosmacheva E.A. BRAIN BLOOD FLOW EXAMINATION WITH HIGH-FLOOR MRI-PERFUSION DURING THE ATTACK OF MIGRAINE WITHOUT AURA. Epilepsy and paroxysmal conditions. 2012;4(4):12-17. (In Russ.)
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