SOMATIC COMORBID ITY AND DE VELOPIN G EPILEPSY IN CHILDREN AFTER A SINGLE SEI ZURE
https://doi.org/10.17749/2077-8333.2017.9.4.006-011
Abstract
Aim – to study chronic somatic comorbidity as a possible predictor of epilepsy in children after a single seizure.
Materials and methods. Based on the follow-up results, 279 cases were studied and compared: the study group – epilepsy – included 166 children with two or more seizures developed at least 24 hours after the first seizure; the control group – 113 children with a single seizure that remained isolated for the subsequent three years.
Results. We found that at the time of the first (single) attack, the background of chronic ocular morbidity (myopia, hypermetropia, optic nerve atrophy, retinal dystrophy) was significantly more common among children in the control group as compared with the confirmed epilepsy group where cardiovascular disorders prevailed. Other concomitant diseases had no statistically significant correlations with the occurrence of epilepsy after a single seizure.
Conclusion. Diagnosis of somatic comorbidity in children with a single seizure may be a prognostic factor of subsequent epilepsy.
About the Authors
L. V. Shalkevich
Belarusian Medical Academy of Postgraduate Education
Belarus
Belarus
Shalkevich Leonid Valentinovich – PhD, Head of the Department of Pediatric Neurology.
Ul. Petrusja Brovki, 3-3, Minsk, 220013, Tel/fax: +375 17 233 55 22
A. I. Kudlatch
Belarusian Medical Academy of Postgraduate Education
Belarus
Belarus
Kudlatch Alisa Igorevna – Clinical resident at the Department of Pediatric Neurology.
Ul. Petrusja Brovki, 3-3, Minsk, 220013, Tel/fax: +375 17 233 55 22
References
1. Sherman E. M.S., Slick D. J., Connolly M. B. et al. ADHD, neurological correlates and health-related quality of life in severe pediatric epilepsy. Epilepsia. 2007; 48 (6): 1083-1091.
2. Elliott J. O., Lu B., Shneker B., Charyton C. et al. Comorbidity, health screening, and quality of life among persons with a history of epilepsy. Epilepsy Behav. 2009; 14 (1): 125-129.
3. Gaitatzis A., Carroll K., Majeed A. et al. The epidemiology of the comorbidity of epilepsy in the general population. Epilepsia. 2004; 45 (12): 1613-1622.
4. Strine T. W., Kobau R., Chapman D. R. et al. Psychological distress, comorbidities, and health behaviors among US adults with seizures. Epilepsia. 2005; 46 (7): 1133-1139.
5. Telez-Zenteno J., Dhar R, Hernandez- Ronquillo L. et al. Long-term outcomes in epilepsy surgery: antiepileptic drugs, mortality, cognitive and psychosocial aspects. Brain. 2007; 130 (2): 334-345.
6. Mar’enko L. B. Zhurnal nevrologii i psikhiatrii (in Russian). 2013; 10: 60-62.
7. Melikyan E. G., Gekht A. B. Zhurnal nevrologii i psikhiatrii (in Russian). 2011; 1: 91-97.
8. Leidy N. K., Elixhauser A., Vickrey B. et al. Seizure frequency and the health-related quality of life of adults with epilepsy. Neurology. 1999; 53 (1): 162-166.
9. Babu C. S., Satishchandra P., Sinha S. et al. Co-morbidities in people living with epilepsy: hospital based case-control study from a resource-poor setting. Epilepsy Res. 2009; 86 (2): 146-152.
10. Ottman R., Lipton R. B., Ettinger A. B. et al. Comorbidities of epilepsy: Results from the Epilepsy Comorbidities and Health (EPIC) survey. Epilepsia. 2011; 52: 308-315.
11. Téllez-Zenteno J.F., Matijevic S., Wiebe S. Somatic comorbidity of epilepsy in the general population in Canada. Epilepsia. 2005; 46 (12): 1955-1962.
12. Maryenko L. B. Comorbidity in epilepsy: etiology, complications or a concomitant disease? Epilepsia. 2005; 46 (6): 299-300.
13. Wiebe S., Hesdorffer D. C. Epilepsy: being ill in more ways than one. Epilepsy Curr. 2007; 7 (6): 145-148.
14. Shal’kevich L.V., Sharko E. E. Neirokhirurgiya i nevrologiya detskogo vozrasta (in Russian). 2014; 3 (41): 49-59.
15. Galanopoulou A. S., Buckmaster P. S., Staley K. J. et al. Identification of new epilepsy treatments: Issues in preclinical methodology. Epilepsia. 2012; 53: 571-582.
16. Karlov V. A. Epilepsy in children and adult women and men: A guide for doctors [Epilepsiya u deteĭ i vzroslykh zhenshchin I muzhchin: Rukovodstvo dlya vracheii (in Russian)]. Moscow. 2010; 538-543.
17. Campbell-Scherer D. Multimorbidity: a challenge for evidence-based medicine. Evid Based Med. 2010; 15: 165-166.
18. Meier C., Kraenzlin M. E. Antiepileptics and bone health. Ther Adv Musculoskelet Dis. 2011; 3 (5): 235-243.
19. Ovchinnikova A. A., Arkhipenko I. V. TMZh (in Russian). 2013; 3 (53): 29-32.
20. Khasanova D. R., Danilova T. V., Latypova Z. K. Kazanskii meditsinskii zhurnal (in Russian). 2013; 2: 235-239.
21. Kalinin V. A., Yakunina A. V., Poverennova I . E. Nevrologiya, neiropsikhiatriya, psikhosomatika (in Russian). 2015; 1: 26-30.
22. Zykov V. P., Mosin I. M., Safronov D. L. et al. Lechebnoe delo (in Russian). 2010; 3: 74-78.
23. Zykov V. P., Mosin I. M., Safronov D. L. et al. Epilepsiya i paroksizmal’nye sostoyaniya / Epilepsy and paroxysmal conditions (in Russian). 2009; 1: 14-20.
Review
For citations:
Shalkevich L.V., Kudlatch A.I. SOMATIC COMORBID ITY AND DE VELOPIN G EPILEPSY IN CHILDREN AFTER A SINGLE SEI ZURE. Epilepsy and paroxysmal conditions. 2017;9(4):6-11. (In Russ.) https://doi.org/10.17749/2077-8333.2017.9.4.006-011
Views: 544
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Email this article 
