MICROSTRUCTURAL AND FUNCTIONAL ABNORMALITIES IN THE BRAIN OF PATIENTS WITH TEMPORAL LOBE EPILEPSY AS REVEALED WITH MR IMAGING
Abstract
Diagnosis of epilepsy remains a challenging task facing physicians of various specialties. When epilepsy is suspected, neuroimaging is one of the major diagnostic tests able to localize the epileptic site and identify the underlying pathology; this information is indispensable in making the diagnosis and predicting the prognosis of the disease. Magnetic resonance imaging (MRI) is the most common modality widely used due to its high sensitivity and specificity in detecting of subtle abnormalities in the brain structure. In addition to the structural pulse sequences, the epilepsy-specific MRIprotocol incorporates a number of recently introduced techniques for the assessment of local functional abnormalities. In this report, the epilepsy-specific protocol that includes the updated pulse sequences technique was used in patients suspected of having temporal lobe epilepsy. Using this technique, characteristic changes in the structure and function of local brain segments in temporal epilepsy were demonstrated.
About the Authors
E. M. Perepelova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Perepelova Elena Mikhailovna – MD, PhD, Head of the Department of Radiology.
Ul. Trubetskaya, 8-2, Moscow, 119048
V. A. Perepelov
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia; Russian Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
Perepelov Vsevolod Andreevich – MD, Medical Resident.
Ul. Barrikadnaya, 2/1, Moscow, 125993
M. S. Merkulova
Russian Medical Academy of Postgraduate Education
Russian Federation
Russian Federation
Merkulova Mariya Sergeevna – MD, Medical Resident.
Ul. Barrikadnaya, 2/1, Moscow, 125993
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For citation:
Perepelova E.M., Perepelov V.A., Merkulova M.S. MICROSTRUCTURAL AND FUNCTIONAL ABNORMALITIES IN THE BRAIN OF PATIENTS WITH TEMPORAL LOBE EPILEPSY AS REVEALED WITH MR IMAGING. Epilepsy and paroxysmal conditions. 2017;9(4):41-49. (In Russ.) https://doi.org/10.17749/2077-8333.2017.9.4.041-049
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