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Epilepsia and paroxyzmal conditions

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CLINICAL, NEURO-PHYSIOLOGICAL AND NEURO-VISUAL ANALYSIS OF ADULT PATIENTS WITH FOCAL EPILEPSY AND ABNORMALITIES OF CARDIAC RHYTHM AND CONDUCTION IN THE ICTAL PERIOD

https://doi.org/10.17749/2077-8333.2018.10.1.014-024

Full Text:

Abstract

Objective. To conduct a survey of adult patients with focal epilepsy and ictal disturbances of cardiac rhythm and conduction, considering the disease classification, anamnesis, clinical, electroencephalographic and neuroimaging data.

Materials and methods. We selected 70 patients aged 18 to 51 years old with confirmed diagnoses of focal epilepsy with epileptic seizures persisting at the time of the study on the background of antiepileptic therapy without concomitant cardiac disorders but with confirmed ictal changes in the cardiac rhythm and conduction.

Results. Among the examined patients, those with long lasting “structural focal epilepsy”, frequent epileptic attacks, temporal and frontal-temporal epileptogenic foci, taking several antiepileptic drugs, prevailed. Most of the heart rhythm and conduction abnormalities occurred in male patients with serial paroxysms, bilateral tonic-clonic seizures, or sleep seizures.

Сonclusion. The timely detection and examination of patients with high risk of ictal arrhythmias is able to prevent disturbances of cardiac rhythm and heart conduction during epileptic seizures, including those with a life-threatening potential. 

About the Authors

Y. V. Rubleva
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

Postgraduate student,

1 Ostrovityanova Str., Moscow 117997



R. A. Teryan
National medical research center of preventive medicine of the Ministry of health of the Russian Federation
Russian Federation

Graduate student,

Petroverigskii pereulok, 10-3, Moscow 101100



G. G. Avakyan
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

MD, PhD, Associate Professor at the Department of Neurology, Neurosurgery and Medical Genetics,

1 Ostrovityanova Str., Moscow 117997



A. A. Savenkov
Zhadkevich Clinical Hospital, Department of Health, the City of Moscow
Russian Federation

MD, PhD, Head of the Inter-branch Department of Paroxysmal Conditions



Y. V. Solomatin
The District Healthcare Facility “Diagnostic clinical center No. 1 with the Department of Healthcare of Moscow”
Russian Federation
MD, PhD, Expert in Paroxysmal Diseases


O. M. Oleynikova
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

MD, PhD, Associate Professor at the Department of Neurology, Neurosurgery and Medical Genetics,

1 Ostrovityanova Str., Moscow 117997



A. M. Teplysheva
The District Healthcare Facility “Diagnostic clinical center No. 62 with the Department of Healthcare of Moscow”
Russian Federation
MD, PhD, Expert in Paroxysmal Diseases


M. B. Mironov
Medical Center for Pediatric Neurology and Pediatrics
Russian Federation

PhD, Head of Laboratory at the Medical Center for Pediatric Neurology and Pediatrics,

13/32 Andropov Avenue, Moscow 101100



T. M. Krasilshchikova
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

Assistant, Chair of Neurology, Neurosurgery and Medical Fenetics, Faculty of Pediatrics,

1 Ostrovityanova Str., Moscow 117997



S. G. Burd
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

MD, PhD, Professor at the Chair of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics,

1 Ostrovityanova Str., Moscow 117997



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For citation:


Rubleva Y.V., Teryan R.A., Avakyan G.G., Savenkov A.A., Solomatin Y.V., Oleynikova O.M., Teplysheva A.M., Mironov M.B., Krasilshchikova T.M., Burd S.G. CLINICAL, NEURO-PHYSIOLOGICAL AND NEURO-VISUAL ANALYSIS OF ADULT PATIENTS WITH FOCAL EPILEPSY AND ABNORMALITIES OF CARDIAC RHYTHM AND CONDUCTION IN THE ICTAL PERIOD. Epilepsia and paroxyzmal conditions. 2018;10(1):14-24. (In Russ.) https://doi.org/10.17749/2077-8333.2018.10.1.014-024

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)