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Epilepsy and paroxysmal conditions

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Epilepsy in children with lymphoproliferative syndrome

https://doi.org/10.17749/2077-8333.2018.10.2.083-094

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Abstract

There are considerable variations in the reported incidence of early and late epilepsy in children with lymphoproliferative diseases. The etiology of seizures in pediatric patients with hemoblastosis during  polychemotherapy can be diverse: dysmetabolic, infectious, toxic, ischemic, posthemorrhagic. The  treatment strategy selected by the neurologist largely depends on the causes of the paroxysmal  conditions. When choosing the anti-seizure therapy one should consider the course of hemoblastoses  and the possible effects of polychemotherapy. The article presents pediatric cases and the analysis of acute lymphoblastic leukemia with developing epileptic seizures.

About the Authors

I. O. Schederkina
Morozov Children’s Clinical Hospital
Russian Federation

1/9 Dobryninskiy 4-y per., Moscow 119049, Russia

MD, PhD, Neurologist, Head of the Center for the Treatment of Cerebrovascular Diseases in Children and Adolescents, Morozov Children’s Clinical Hospital



O. A. Tiganova
Morozov Children’s Clinical Hospital N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

1/9 Dobryninskiy 4-y per., Moscow 119049, Russia

1 Ostrovityanova Str., Moscow 117997, Russia

MD, PhD, Chief External Oncologist at the Moscow City Department of Healthcare; Hematologist- oncologist, Morozov Children’s Clinical Hospital; Associate Professor at the Department of  Pediatrics, N. I. Pirogov Russian National Research Medical University. Tel.: +7 (499) 236-24-02



I. E. Koltunov
Morozov Children’s Clinical Hospital
Russian Federation

1/9 Dobryninskiy 4-y per., Moscow 119049, Russia

MD, Honored Medical Doctor of Russia, Professor, Chief Physician, Morozov Children’s Clinical Hospital. Tel.: +7 (499) 236-24-02



N. V. Natrusova
Morozov Children’s Clinical Hospital
Russian Federation

1/9 Dobryninskiy 4-y per., Moscow 119049, Russia

MD, Neurologist, Morozov Children’s Clinical Hospital. Tel.: +7 (495) 959-88-00



K. L. Kondratchik
Morozov Children’s Clinical Hospital
Russian Federation

1/9 Dobryninskiy 4-y per., Moscow 119049, Russia

MD, PhD, Head of the Center for Pediatric Oncology and Hematology, Head of the Department of  Oncology and Hematology, Morozov Children’s Clinical Hospital, Associate Professor at the  Department of Oncology, Hematology and Immunology, N. I. Pirogov Russian National Research Medical University. Tel.: +7 (499) 236-24-02



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For citation:


Schederkina I.O., Tiganova O.A., Koltunov I.E., Natrusova N.V., Kondratchik K.L. Epilepsy in children with lymphoproliferative syndrome. Epilepsy and paroxysmal conditions. 2018;10(2):82-94. (In Russ.) https://doi.org/10.17749/2077-8333.2018.10.2.083-094

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)