Preview

Epilepsy and paroxysmal conditions

Advanced search

Paroxysmal disorders in the long-term after traumatic brain injury in children and adolescents

https://doi.org/10.17749/2077-8333.2018.10.4.072-082

Full Text:

Abstract

Consequences of traumatic brain injury (TBI) in children and adolescents pose a major medical and social problem, as TBI interferes with neuro ontogenesis. Among these consequences, paroxysmal disorders that manifest in the long-term after TBI represent an important issue. These disorders include posttraumatic headaches, posttraumatic epilepsy and subclinical epileptiform EEG activity. In this review, clinical manifestations, pathophysiology and management of the long-term post-TBI paroxysmal disorders in children and adolescents are discussed.

About the Authors

N. N. Zavadenko
Pirogov Russian National Research Medical University.
Russian Federation

Nikolay N. Zavadenko – MD, PhD, Professor & Head, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics.

1 Ostrovityanova Str., Moscow 117997.

Tel.: +7(495)936-94-52.

Scopus Author ID: 7004071775.



Yu. E. Nesterovskiy
Pirogov Russian National Research Medical University.
Russian Federation

Yuriy E. Nesterovskiy – MD, PhD, Associate Professor, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics.

1 Ostrovityanova Str., Moscow 117997.


A. A. Kholin
Pirogov Russian National Research Medical University.
Russian Federation

Alexey A. Kholin – MD, PhD, Professor, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics.

1 Ostrovityanova Str., Moscow 117997.



I. S. Vorobyeva
Pirogov Russian National Research Medical University.
Russian Federation

Irina S. Vorobyeva – MD, Neurologist, PhD student, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics.

1 Ostrovityanova Str., Moscow 117997.


References

1. Zavadenko N. N., Nemkova S. A. Disorders of development and cognitive dysfunction in children with diseases of the nervous system. Scientific and practical guide. Moscow. 2016; 360 s. (in Russian).

2. Lixterman L. B. Traumatic brain injury. Diagnosis and treatment. Moscow. 2014; 488 s. (in Russian).

3. Zhivolupov S. A., Samarcev I. N., Bardakov S. N. Rational neuroprotection in traumatic brain disease. Moscow. 2014; 176 s. (in Russian).

4. Konovalov A. N., Lixterman L. B., Potapov A. A. et al. Clinical guide to traumatic brain injury. Moscow. 1998; 1: 549 s. (in Russian).

5. Kolb B. Brain plasticity and behavior during development. In: Uzzell B.P, editor. Recovery after Traumatic Brain Injury. Psychology Press. 2014; 199-212.

6. Christensen J. R., Trovato M. K., Salorio C., Brandys E., Morozova O., Sadowsky C., Pidcock F. S. Traumatic Brain Injury. In: Neurodevelopmental Disabilities in Infancy and Childhood. 3-rd ed. Ed. P. J. Accardo. Baltimore. 2008; 615-637.

7. Su Y. R.S., Veeravagu A., Grant G. Neuroplasticity after Traumatic Brain Injury. In: Laskowitz D, Grant G (Eds.), Translational Research in Traumatic Brain Injury. Chapter 8, Frontiers in Neuroscience. CRC Press/Taylor and Francis Group, Boca Raton, Florida. 2016; 163-178.

8. Zavadenko N. N., Kemalov A. I. The consequences of severe traumatic brain injury in children and their treatment. Voprosy sovremennoj pediatrii. 2006; 5 (4): 14-21. (in Russian).

9. Zavadenko N. N., Guzilova L. S., Iznak A. F., Iznak E. V. The consequences of severe traumatic brain injury in adolescents: features of clinical manifestations and treatment. Voprosy sovremennoj pediatrii. 2010; 9 (4): 57-67 (in Russian).

10. Sady M. D., Vaughan C. G., Gioia G. A. Psychometric characteristics of the postconcussion symptom inventory in children and adolescent s. Archives of Clinical Neuropsychology. 2014; 29 (4): 348-363. DOI: https://doi.org/10.1093/arclin/acu014.

11. MKB-10 – International Classification of Diseases (10th revision). Classification of mental and behavioral disorders. Research diagnostic criteria. SPb: WHO, 1994; 208 s. (in Russian).

12. The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018; 38 (1): 1-211. DOI: 10.1177/0333102417738202.

13. Shaw L., Morozova M., Abu-Arafeh I. Chronic post-traumatic headache in children and adolescents: systematic review of prevalence and headache features. Pain Manag. 2018; 8 (1): 57-64. DOI: 10.2217/pmt-2017-0019.

14. Mayer C. L., Huber B. R., Peskind E. Traumatic brain injury, neuroinflammation, and post-traumatic headaches. Headache. 2013; 53 (9): 1523-1530. DOI: 10.1111/head.12173.

15. Vorob’eva O.V., Vejn A. M. Post Traumatic Headaches. Consilium medicum. 1999; 1 (2): 73-75. (in Russian).

16. Myakotnyx V. S., Talankina N. Z., Borovkova T. A. Clinical, pathophysiological and morphological aspects of the remote period of a closed head injury. Zhurnal nevrologii i psixiatrii im. S. S. Korsakova. 2002; 102 (4): 61-65. (in Russian).

17. Goryunova A. V. Post-traumatic headache in children. Zhurn. nevrologii i psixiatrii im. S. S. Korsakova. 2009; 109 (12): 55-59. (in Russian).

18. Bazarnaya N. A. Chronic post-traumatic headache in children. PhD diss. Moscow. 2004; 25 s. (in Russian).

19. Guzilova L. S. The consequences of severe closed head injury and evaluation of the effectiveness of their treatment with nootropic drugs in adolescents. PhD diss. Moscow. 2008; 31 s. (in Russian).

20. Cooper D. W., Cavicke D. C. Post-traumatic headache and epilepsy. Report of two cases suggesting possible relationship. Conn Med. 1963; 27: 131-133.

21. Formisano R., Bivona U., Catani S., D’Ippolito M., Buzzi M. G. Posttraumatic headache: facts and doubts. J Headache Pain. 2009; 10 (3): 145-152.DOI: 10.1007/s10194-009-0108-4.

22. Kontos A. P., Reches A., Elbin R. J., Dickman D., Laufer I., Geva A. B., Shacham G., DeWolf R., Collins M. W. Preliminary evidence of reduced brain network activation in patients with post-traumatic migraine following concussion. Brain Imaging Behav. 2016; 10 (2): 594-603. DOI: 10.1007/s11682-015-9412-6.

23. Ajkardi Zh., Baks M., Gillberg K. Diseases of the nervous system in children. Translation from English by ed. A. A. Skoromets. Moscow. 2013; 26: 761-762. (in Russian).

24. Englander J., Bushnik T., Duong T., Cifu D. X., Zafonte R., Wright J., Hughes R., Bergman W. Analyzing risk factors for late posttraumatic seizures: A prospective, Multicenter Investigation. Arch Phys Med Rehabil. 2003; 84 (3): 365-373. DOI: 10.1053/apmr.2003.50022.

25. Ding K., Gupta P. K., Diaz-Arrastia R. Epilepsy after Traumatic Brain Injury. In: Laskowitz D., Grant G. (Eds.). Translational Research in Traumatic Brain Injury. Chapter 14, Frontiers in Neuroscience. CRC Press/Taylor and Francis Group, Boca Raton, Florida. 2016; 299-314.

26. Cansu A., Serdaroğlu A., Yüksel D., Doğan V., Ozkan S. et al. Prevalence of some risk factors in children with epilepsy compared to their controls. Seizure. 2007; 16 (4): 338-344. DOI: 10.1016/j.seizure.2007.02.003.

27. Appleton R. E., Demellweek C. Post-traumatic epilepsy in children requiring inpatient rehabilitation following head injury. J. Neurol. Neurosurg. Psychiatry. 2002; 72 (5): 669-672.

28. Frey L. C. Epidemiology of posttraumatic epilepsy: A critical review. Epilepsia. 2003; 44 (10): 11-17.

29. Annegers J. F., Hauser W. A., Coan S. P., Rocca W. A. A populationbased study of seizures after traumatic brain injuries. N Engl J Med. 1998; 338 (1): 20-24.

30. Asikainen I., Kaste M., Sarna S. Early and late posttraumatic seizures in traumatic brain injury rehabilitation patients: brain injury factors causing late seizures and influence of seizures on long-term outcome. Epilepsia. 1999; 40 (5): 584-589.

31. Statler K. D. Pediatric posttraumatic seizures: epidemiology, putative mechanisms of epileptogenesis and promising investigational progress. Dev Neurosci. 2006; 28 (4-5): 354-363. DOI: 10.1159/000094162.

32. Curia G., Eastman C. L., Miller J. W., D’Ambrosio R. Modeling Post-Traumatic Epilepsy for Therapy Development. In: Laskowitz D, Grant G (Eds.), Translational Research in Traumatic Brain Injury. Chapter 10, Frontiers in Neuroscience. CRC Press/Taylor and Francis Group, Boca Raton, Florida. 2016; 219-238.

33. Hung C. H., Chen J. W. Y. Treatment of Post-Traumatic Epilepsy. Current Treatment Options in Neurology. 2012; 14 (4): 293-306. DOI: 10.1007/s11940-012-0178-5.

34. D’Ambrosio R., Perucca E. Epilepsy after head injury. Current Opinion in Neurology. 2004; 17 (6): 731-735.

35. Cottera D., Kelsoa A., Neligana A. Genetic biomarkers of posttraumatic epilepsy: a systematic review. Seizure. 2017; 46: 53-58. DOI: 10.1016/j.seizure.2017.02.002.

36. Arndt D. H., Lerner J. T., Matsumoto J. H., Madikians A., Yudovin S., Valino H., McArthur D. L., Wu J. Y., Leung M., Buxey F., Szeliga C., Van Hirtum-Das M., Sankar R., Brooks-Kayal A., Giza C. C. Subclinical early posttraumatic seizures detected by continuous EEG monitoring in a consecutive pediatric cohort. Epilepsia. 2013; 54 (10): 1780-1788. DOI: 10.1111/epi.12369.

37. Miller G. S. Efficacy and safety of levetiracetam in pediatric migraine. Headache. 2004; 44 (3): 238-243.

38. Pakalnis A., Kring D., Meier L. Levetiracetam prophylaxis in pediatric migraine – an open-label study.Headache. 2007; 47 (3): 427-430. DOI: 10.1111/j.1526-4610.2007.00728.x.

39. Awaad Y., Rizk T. Levetiracetam in the treatment of pediatric headache. Journal of Taibah University Medical Sciences. 2014; 9 (1): 74-77. DOI: 10.1016/j.jtumed.2013.05.004.

40. Lindholm DL. Levetiracetam levels correlating with successful treatment of epilepsy and migraine, cognitive effects and adverse reactions in the pediatric age group. Epilepsia. 2002; 43 (7): 60.

41. Meshkini A., Ghojazadeh M., Golbahar-Haghighi A., Zarea-Gavgani V., Lotfi-Sadigh S. Comparison of levetiracetam versus phenytoin for seizure prophylaxis in patients with traumatic brain injury: A meta-analysis. J Anal Res Clin Med. 2015; 3 (2): 118-125. DOI: 10.15171/jarcm.2015.018.

42. Shetty A. K. Prospects of levetiracetam as a neuroprotective drug against status epilepticus, traumatic brain injury, and stroke. Front Neurol. 2013; 4: 172. DOI: 10.3389/fneur.2013.00172.

43. Zavadenko N. N., Xolin A. A., Orlova E. V., Proskuryakov K. V. Posttraumatic epilepsy in children and adolescents. Farmateka. 2014; 1 (274): 18-22. (in Russian).

44. Pearl P. L., McCarter R., McGavin C.L. et al. Results of phase II levetiracetam trial following acute head injury in children at risk for posttraumatic epilepsy. Epilepsia. 2013, 54 (9): 135-137. DOI: 10.1111/epi.12326.


For citation:


Zavadenko N.N., Nesterovskiy Y.E., Kholin A.A., Vorobyeva I.S. Paroxysmal disorders in the long-term after traumatic brain injury in children and adolescents. Epilepsy and paroxysmal conditions. 2018;10(4):72-82. (In Russ.) https://doi.org/10.17749/2077-8333.2018.10.4.072-082

Views: 105


ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)