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Epilepsy in Sturge-Weber syndrome: a literature review and description of a clinical case

https://doi.org/10.17749/2077-8333.2020.12.1.67-73

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Abstract

The Struge-Weber syndrome is the third most common neurodermal disease after neurofibromatosis and tuberous sclerosis. This disease is not inherited, but occurs exclusively sporadically, both in men and in women, and in all races and ethnic groups. In 90% of cases, this syndrome is diagnosed in pediatric practice. Adult cases of this syndrome are sporadic, since they remain unrecognized due to the polymorphism of this disease. Comorbidity between epilepsy and the Sturge-Weber syndrome was noted.

Aim. To conduct a literature analysis and describe the clinical observation of epilepsy with the Sturge-Weber syndrome.

Materials and methods. Patient M., 50 years old has been observed for a long time due to complaints on episodes of numbness according to the hematotype with transient paresis. The examination (MRI) revealed changes characteristic for Sturge-Weber syndrome. The presence of specific paroxysmal changes according to the results of electroencephalography helped to verify the genesis of paroxysmal conditions.

Results. The patient underwent a comprehensive examination. As a result, the diagnosis of epilepsy was verified. The prescription of adequate antiepileptic therapy allowed for stabilization and jugulation of epileptic seizures.

Conclusion. In this clinical observation, we focus on the differential diagnosis between transient ischemic attack and epilepsy. Unfortunately, at the moment, adults with a previously undetectable syndrome undergo multiple hospitalizations and do not receive antiepileptic therapy, since the prior disease (epilepsy) is not verified.

About the Authors

N. I. Shova
Bekhterev National Medical Research Center of Psychiatry and Neurology
Russian Federation

graduate student,

3 Bekhtereva Str., Saint Petersburg 192019, Russia



V. A. Mikhailov
Bekhterev National Medical Research Center of Psychiatry and Neurology
Russian Federation

MD, Dr Sci Med, Vice-director for innovative scientific development and international cooperation, Head of the international department, Chief researcher and Scientific director of the Department for the treatment of organic mental disorders and epilepsy and rehabilitation of patients with psychosomatic disorders,

3 Bekhtereva Str., Saint Petersburg 192019, Russia



S. A. Korovina
Bekhterev National Medical Research Center of Psychiatry and Neurology
Russian Federation

MD, PhD, Head of the Department for the treatment of organic mental disorders/epilepsy,

3 Bekhtereva Str., Saint Petersburg 192019, Russia



D. V. Alekseeva
Bekhterev National Medical Research Center of Psychiatry and Neurology
Russian Federation

Junior Researcher, 7th Department,

3 Bekhtereva Str., Saint Petersburg 192019, Russia



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For citation:


Shova N.I., Mikhailov V.A., Korovina S.A., Alekseeva D.V. Epilepsy in Sturge-Weber syndrome: a literature review and description of a clinical case. Epilepsy and paroxysmal conditions. 2020;12(1):67-73. (In Russ.) https://doi.org/10.17749/2077-8333.2020.12.1.67-73

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)