COMPARATIVE EVALUATION OF THE EFFICACY AND SAFETY OF VALPROIC ACID DERIVATIVES
Abstract
Abstract: this article discusses the comparative efficacy and safety of valproic acid derivatives (various salts), and the original of generic drugs based on it, are the literature data and the results of our experimental and clinical studies on the interchangeability of original and generic drugs – valproic acid derivatives, in particular Depakin Chrono, Convulex Retard, Valparin XP and Enkorat Chrono. The results of the research, conclusions were drawn, which essentially boils down to if inability to provide original drugs, a transition to generic valproic acid, in particular Enkorat Chrono, is possible.
About the Authors
O. L. Badalyan
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
S. G. Burd
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
A. A. Savenkov
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
G. G. Avakyan
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
E. V. Yutskova
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
G. N. Avakyan
Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Badalyan O.L., Burd S.G., Savenkov A.A., Avakyan G.G., Yutskova E.V., Avakyan G.N. COMPARATIVE EVALUATION OF THE EFFICACY AND SAFETY OF VALPROIC ACID DERIVATIVES. Epilepsy and paroxysmal conditions. 2014;6(2):39-44. (In Russ.)
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