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NEUROPHYSIOLOGICAL AND PSYCHOPATHOLOGICAL ASPECTS OF EPILEPSY IN ELDERLY

https://doi.org/10.17749/2077-8333.2016.8.1.029-036

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Abstract

In the past decades, an increasing incidence and prevalence of epilepsy in older age groups. Neurophysiological constants of the usual analysis of the EEG in this age group of patients is quite contradictory and inconclusive.

Objective: to determine the most specific EEG-patterns, according to the spectral analysis of coherence and capacity in patients with epilepsy elderly, to identify correlations and neurophysiological data of emotional-affective disorders.

Materials and methods: we Studied 182 patients older, and of these, 142 respectively with the effects of organic lesions of the brain, in 101 patients the disease was complicated by symptomatic epilepsy local. All patients underwent EEG with subsequent processing by the method of coherent analysis. 142 patients with organic and vascular pathology clinical and psychological testing with the use of scales and questionnaires (SF-36,QOLIE-31, SCL-90-R, BDI, HRDS, STAI).

Results: In patients with epilepsy elderly according to the spatial temporal analysis formed persistent «pathological», coherent communication in the Delta and theta bands of the EEG nterhemispheric formation of contacts (T6-P3, T4-T3, P4-O1),
the increase in the number of these links in the rear temporal region, the anterior frontal right, parietal left (T6,T5, F8,P3).
Neurophysiological value analysis confirm the presence of depressive and anxiety disorders in this group of patients (depression in 56,3% of patients with epilepsy, anxiety disorder in 8.7% of MCI — 11.7%. Values of indicators of depression on the BDI scale in amounted 34.81±2.73 points, HRDS — of 21.84±1.50).

Conclusion: the materials obtained during the study allow to make a conclusion about some features of spatial-temporal organization of brain biopotentials in patients with epilepsy elderly in comparison with groups of elderly patients without this pathology, and their mutual relation with the severity of psychopathological symptoms.

About the Authors

V. A. Mikhailov
St. Petersburg V. M. Bekhterev Psychoneurological Research Institute
Russian Federation

MD, deputy director of innovative scientific development and international cooperation, the head of the international department, chief researcher and scientific director of department of rehabilitation of patients with psychosomatic disorders, St. Petersburg V. M. Bekhterev sychoneurological Research Institute. Address: ul. Bekhtereva, 3, St. Petersburg, Russia, 192019



A. K. Druzhinin
St. Petersburg V. M. Bekhterev Psychoneurological Research Institute
Russian Federation

Junior Researcher at the Department of rehabilitation of patients with psychosomatic disorders, St. Petersburg V. M. Bekhterev Psychoneurological Research Institute. Address: ul. Bekhtereva, 3, St. Petersburg, Russia, 192019



M. Ya. Kissin
The first St. Petersburg State Medical University named after Academician Pavlov
Russian Federation

MD, Professor of the Department of Psychiatry and Addiction with the rate of general and medical psychology, psychosomatic medicine psychotherapy basics, St. Petersburg V. M. Bekhterev Psychoneurological Research Institute. Address: ul. Bekhtereva, 3, St. Petersburg, Russia, 192019; head of epilepsy centers of St. Petersburg.
Address: Naberezhnaya Obvodnogo kanala, 13, St. Petersburg, Russia, 192019



A. L. Gorelik
St. Petersburg V. M. Bekhterev Psychoneurological Research Institute
Russian Federation

PhD, head of the department of functional diagnostics, Senior Researcher, St. Petersburg V. M. Bekhterev Psychoneurological Research Institute. Address: ul. Bekhtereva, 3, St. Petersburg, Russia, 192019.



V. V. Bocharov
St. Petersburg V. M. Bekhterev Psychoneurological Research Institute
Russian Federation

PhD, St. Petersburg V. M. Bekhterev. Address: ul. Bekhtereva, 3, St. Petersburg, Russia, 192019; head of the laboratory of clinical psychology and psycho-diagnostics, an assistant professor of psychology and extreme states of crisis psychology department. Address: Naberezhnaya Obvodnogo kanala, 13, St. Petersburg, Russia, 192019



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For citation:


Mikhailov V.A., Druzhinin A.K., Kissin M.Y., Gorelik A.L., Bocharov V.V. NEUROPHYSIOLOGICAL AND PSYCHOPATHOLOGICAL ASPECTS OF EPILEPSY IN ELDERLY. Epilepsia and paroxysmal conditions. 2016;8(1):29-36. (In Russ.) https://doi.org/10.17749/2077-8333.2016.8.1.029-036

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)