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Periodic discharges with triphasic morphology: a differential diagnosis and therapeutic approaches

https://doi.org/10.17749/2077-8333/epi.par.con.2021.052

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Abstract

The article presents two clinical cases of intensive care unit (ICU) patients with periodic discharges. Examination according to the American Clinical Neurophysiology Society (ACNS) protocol with the use of electroencephalography and functional probes allows differential diagnosis of periodic discharges, which makes it possible to conduct early pathophysiological treatment, to assess its effectiveness in dynamics and to avoid unjustified prescription of antiepileptic drugs. At the same time, the prognosis of the disease and the effectiveness of treatment are largely determined by the etiology of the disease. Evaluation of periodic discharges of three-phase morphology in ICU, considering its nosological nonspecificity, is rational to carry out according to the ACNS recommendations, indicating the ictal genesis, background activity, response to antiepileptic drugs.

About the Authors

D. S. Kan’shina
Pirogov National Medical and Surgical Center; Clinical and Research Institute of Emergency Pediatric Surgery and Trauma
Russian Federation

Darya S. Kan’shina – MD, PhD, Associate Professor, Chair of Neurology with Neurosurgery Course, Pirogov National Medical and Surgical Center; Head of Department of Neurology and Clinical Neurophysiology, Clinical and Research Institute of Emergency Pediatric Surgery and Trauma

RSCI SPIN-code: 4032-4210

70 Nizhnyaya Pervomayskaya Str., Moscow 105203

22 Bolshaya Polyanka Str., Moscow 119180



I. V. Okuneva
Veltishchev Research Clinical Institute of Pediatrics, Pirogov Russian National Research Medical University
Russian Federation

Irina V. Okuneva – Neurologist, Video-EEG Monitoring Cabinet, Psychoneurological Department No. 1

2 Taldomskaya, Moscow 125412



A. V. Vakhlyaev
Pirogov National Medical and Surgical Center
Russian Federation

Anton V. Vakhlyaev – Anesthesiologist-Resuscitator, Department of Anesthesiology and Resuscitation

RSCI SPIN-code: 4180-0780

70 Nizhnyaya Pervomayskaya Str., Moscow 105203



O. Yu. Bronov
Pirogov National Medical and Surgical Center
Russian Federation

Oleg Yu. Bronov – MD, PhD, Head of Department of Radiology, Associate Professor, Chair of Radiation Diagnostics with a Course of Clinical Radiology

Scopus Author ID: 57215892759; RSCI SPIN-code: 7429-7993

70 Nizhnyaya Pervomayskaya Str., Moscow 105203



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For citation:


Kan’shina D.S., Okuneva I.V., Vakhlyaev A.V., Bronov O.Yu. Periodic discharges with triphasic morphology: a differential diagnosis and therapeutic approaches. Epilepsy and paroxysmal conditions. 2021;13(2):124-131. (In Russ.) https://doi.org/10.17749/2077-8333/epi.par.con.2021.052

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)