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Compliance in epileptology. How to change the situation for better

https://doi.org/10.17749/2077-8333/epi.par.con.2021.059

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Abstract

The problem of low adherence to therapy in patients with epilepsy is one of the most pressing public health problems. Failure to follow the doctor's instructions leads to an increased risk of hospitalization and sudden death. Knowing the main predictors of non-compliance, the doctor is able to develop appropriate strategies to increase adherence. There are methods of improving compliance that should be actively implemented in the clinical practice of epileptologists. The article presents a review of the literature on this problem, clinical examples from the authors' practice are given.

About the Authors

N. N. Maslova
Smolensk State Medical University
Russian Federation

Natalia N. Maslova – Dr. Med. Sc., Professor, Chief of Chair of Neurology and Neurosurgery

Scopus Author ID: 7005487934; RSCI SPIN-code: 4193-3595

28 Krupskaya Str., Smolensk 214019



A. A. Litvinova
Smolensk State Medical University
Russian Federation

Aleksandra A. Litvinova – 4th year Student, Faculty of Therapy

RSCI SPIN-code: 2234-7591

28 Krupskaya Str., Smolensk 214019



N. V. Yuryeva
Smolensk State Medical University
Russian Federation

Natalia V. Yuryeva – MD, PhD, Associate Professor, Chair of Neurology and Neurosurgery

RSCI SPIN-code: 4193-3595

28 Krupskaya Str., Smolensk 214019



P. S. Kovalev
Smolensk State Medical University
Russian Federation

Pavel S. Kovalev – Assistant Professor, Neurology and Neurosurgery

28 Krupskaya Str., Smolensk 214019



References

1. Niriayo Y.L., Mamo A., Gidey K., Demoz G.T. Medication belief and adherence among patients with epilepsy. Behav Neurol. 2019; 2019: 2806341. https://doi.org/10.1155/2019/2806341.

2. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization; 2003.

3. Gromov S.А., Sivakova N.А., Gromova О.А. Mono- and polytherapy of patients with epilepsy. In: 10th Davidenkov Readings. Saint Petersburg; 2018: 103–4 (in Russ.).

4. Avakyan G.N., Belousova E.D., Burd S.G., et al. Current trends in epileptology: priorities, challenges, tasks and solutions. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2019; 11 (4): 395–406 (in Russ.). https://doi.org/10.17749/2077-8333.2019.11.4.395-406.

5. Mikhaylov V.А., Druzhinin А.К., Lipatova L.V., et al. Elderly epilepsy: questions and problems. In: Epileptology in the system of neuroscience. Collection of conference materials. Saint Petersburg; 2015: 132–6 (in Russ.).

6. Vasserman L.I. Psychodiagnostics for epilepsy. Meditsinskaya psikholo review of the international literature. BMJ Open. 2018; 8 (5): e019101. https://doi.org/10.1136/bmjopen-2017-019101.

7. Panferova Е.V., Belousova Е.D. Professional activity of patients with epilepsy: a study of the practice of hiring and working in companies operating in Russia. Vestnik epileptologii / Bulletin of Epileptology. 2020; 1: 55–61 (in Russ.).

8. Belousova Е.D. The problem of compliance in patients suffering from epilepsy. Russian Medical Journal. 2009; 17 (5): 380–3 (in Russ.).

9. Devinsky O., Vezzani A., O'Brien T.J., et al. Epilepsy. Nat Rev Dis Primers. 2018; 4: 18024. https://doi.org/10.1038/nrdp.2018.24.

10. Jetté N., Sander J.W., Keezer M.R. Surgical treatment for epilepsy: the potential gap between evidence and practice. Lancet Neurol. 2016; 15 (9): 982–94. https://doi.org/10.1016/s1474-4422(16)30127-2.

11. Fiest K.M., Sauro K.M., Wiebe S., et al. Prevalence and incidence of epilepsy: a systematic review and meta-analysis of international studies. Neurology. 2017; 88 (3): 296–303. https://doi.org/10.1212/wnl.0000000000003509.

12. Edward K., Cook M., Stephenson J., Giandinoto J.A. The impact of brief lifestyle self-management education for the control of seizures. Brit J Nurs. 2019; 28 (6): 348–54. https://doi.org/10.12968/bjon.2019.28.6.348.

13. Banks J., Varley J., Fitzsimons M., Doherty C.P. Self-reported antiepilepsy medication adherence and its connection to perception of medication error. Epilepsy Behav. 2020; 104 (Pt. A): 106896. https://doi.org/10.1016/j.yebeh.2019.106896.

14. Prell T., Grosskreutz J., Mendorf S., et al. Clusters of non-adherence to medication in neurological patients. Res Social Adm Pharm. 2019; 15 (12): 1419–24. https://doi.org/10.1016/j.sapharm.2019.01.001.

15. Henning O., Johannessen Landmark C., Nakken K.O., Lossius M.I. Nonadherence to treatment regimens in epilepsy from the patient's perspective and predisposing factors: differences between intentional and unintentional lack of adherence. Epilepsia. 2019; 60 (5): e58–62. https://doi.org/10.1111/epi.14734.

16. O’Rourke G., O’Brien J.J. Identifying the barriers to antiepileptic drug adherence among adults with epilepsy. Seizure. 2017; 45: 160–8. https://doi.org/10.1016/j.seizure.2016.12.006.

17. May T.W., Berkenfeld R., Dennig D., et al. Patients’ perspectives on management and barriers of regular antiepileptic drug intake. Epilepsy Behav. 2018; 79: 162–8. https://doi.org/10.1016/j.yebeh.2017.11.039.

18. Piper K., Richman J., Faught E., et al. Adherence to antiepileptic drugs among diverse older Americans on Part D Medicare. Epilepsy Behav. 2017; 66: 68–73. https://doi.org/10.1016/j.yebeh.2016.10.017.

19. Molotkov A.O., Punin A.A., Molotkova S.A., Evseeva I.P. Compliance or patients loyalty to therapy: current situation and feature in bronchial asthma. Vestnik of the Smolensk State Medical Academy. 2012; 11 (1): 56–62 (in Russ.)

20. Assiri G.A., Shebl N.A., Mahmoud M.A., et al. What is the epidemiology of medication errors, error-related adverse events and risk factors for errors in adults managed in community care contexts? A systematic review of the international literature. BMJ Open. 2018; 8 (5): e019101. https://doi.org/10.1136/bmjopen-2017-019101.

21. Mroueh L., Boumediene F., Jost J., et al. Self-reported attitudes about medication in Lebanese people with epilepsy. Epilepsy Behav. 2019; 98 (Pt. A): 80–7. https://doi.org/10.1016/j.yebeh.2019.06.028.

22. Cramer J.A., Wang Z.J., Chang E., et al. Health-care costs and utilization related to longor short-acting antiepileptic monotherapy use. Epilepsy Behav. 2015; 44: 40–6. https://doi.org/10.1016/j.yebeh.2014.12.020.

23. Gollwitzer S., Kostev K., Hagge M., et al. Nonadherence to antiepileptic drugs in Germany: a retrospective, population-based study. Neurology. 2016; 87 (5): 466–72. https://doi.org/10.1212/wnl.0000000000002791.

24. Laville F., Montana M., Roux N., et al. Factors limiting adherence to antiepileptic treatment: a French online patient survey. J Clin Pharm Ther. 2018; 43 (1): 73–9. https://doi.org/10.1111/jcpt.12615.

25. Тeh K.X., Henien N.P., Wong L.S., et al. A cross-sectional study on the rate of non-adherence to anti-seizure medications and factors associated with non-adherence among patients with epilepsy. PLoS One. 2020; 15 (7): e0235674. https://doi.org/10.1371/journal.pone.0235674.

26. Lee H.J., Choi E.K., Park H.B., Yang S.H. Risk and protective factors related to stigma among people with epilepsy: an integrative review. Epilepsy Behav. 2020; 104 (Pt. A): 106908. https://doi.org/10.1016/j.yebeh.2020.106908.

27. Сrooks R.E., Bell M., Patten S.B., et al. Mind the gap: exploring information gaps for the development of an online resource hub for epilepsy and depression. Epilepsy Behav. 2017; 70 (Pt. A): 18–23. https://doi.org/10.1016/j.yebeh.2017.03.005.

28. Shi Y., Wang S., Ying J., et al. Correlates of perceived stigma for people living with epilepsy: a meta-analysis. Epilepsy Behav. 2017; 70: 198–203. https://doi.org/10.1016/j.yebeh.2017.02.022.

29. Ridsdale L., Wojewodka G., Robinson E., et al. Characteristics associated with quality of life among people with drug-resistant epilepsy. J Neurol. 2017; 264 (6): 1174–84. https://doi.org/10.1007/s00415-017-8512-1.

30. Rassart J., Luyckx K., Verdyck L., et al. Personality functioning in adults with refractory epilepsy and community adults: Implications for health-related quality of life. Epilepsy Res. 2020; 159: 106251. https://doi.org/10.1016/j.eplepsyres.2019.106251.

31. Centers For Disease Control And Prevention Epilepsy Program. Available at: https://www.epilepsy.com/sites/core/files/atoms/files/CDC_0.pdf (accessed 15.05.2021).

32. Maslova N.N., Skorobogatova V.A. Compliance in epileptology: a modern view of the problem and strategies for its optimization. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2020; 12 (1): 74–811 (in Russ.). https://doi.org/10.17749/2077-8333.2020.12.1.74-81.

33. England M.J., Liverman C.T., Schultz A.M., Strawbridge L.M. (Eds.) Epilepsy across the spectrum: promoting health and understanding. Washington (DC): National Academies Press (US); 2012. https://doi.org/10.17226/13379.

34. Yeni K., Tulek Z., Bebek N., et al. Attitudes towards epilepsy among a sample of Turkish patients with epilepsy. Epilepsy Behav. 2016; 62: 66–71. https://doi.org/10.1016/j.yebeh.2016.06.022.

35. Yeni K., Tulek Z., Simsek O.F., Bebek N. Relationships between knowledge, attitudes, stigma, anxiety and depression, and quality of life in epilepsy: a structural equation modeling. Epilepsy Behav. 2018; 85: 212–7. https://doi.org/10.1016/j.yebeh.2018.06.019.

36. Ozuna J., Kelly P., Towne A., Hixson J. Self-management in epilepsy care: untapped opportunities. Fed Pract. 2018; 35 (Suppl. 3): S10–6.

37. Pandey D.K., Dasgupta R., Levy J., et al. Enhancing epilepsy selfmanagement and quality of life for adults with epilepsy with varying social and educational backgrounds using PAUSE to Learn Your Epilepsy. Epilepsy Behav. 2020; 111: 107228. https://doi.org/10.1016/j.yebeh.2020.107228.

38. Pandey D.K., Levy J., Serafini A., et al. Self-management skills and behaviors, self-efficacy, and quality of life in people with epilepsy from underserved populations. Epilepsy Behav. 2019; 98 (Pt. A): 258–65. https://doi.org/10.1016/j.yebeh.2019.07.042.

39. Gandy M., Karin E., McDonald S., et al. A feasibility trial of an internet-delivered psychological intervention to manage mental health and functional outcomes in neurological disorders. J Psychosom Res. 2020; 136: 110173. https://doi.org/10.1016/j.jpsychores.2020.110173.

40. Saengow V.E., Chancharoenchai P., Saartying W., et al. Epilepsy video animation: impact on knowledge and drug adherence in pediatric epilepsy patients and caregivers. Clin Neurol Neurosurg. 2018; 172: 59–61. https://doi.org/10.1016/j.clineuro.2018.06.031.

41. Schachter S.C. Overview of the management of epilepsy in adults. Available at: https://www.uptodate.com/contents/overview-of-themanagement-of-epilepsy-in-adults (accessed 15.05.2021).

42. Karlov V.A. Epilepsy in children and adult women and men. A guide for doctors. 2nd ed. Мoscow: BINOM; 2019 (in Russ.).

43. Michaelis R., Tang V., Goldstein L.H., et al. Psychological treatments for adults and children with epilepsy: evidence-based recommendations by the International League Against Epilepsy Psychology Task Force. Epilepsia. 2018; 59: 1282–302. https://doi.org/10.1111/epi.14444.

44. Sihvonen A.J., Särkämö T., Leo V., et al. Music-based interventions in neurological rehabilitation. Lancet Neurol. 2017; 16 (8): 648–60. https://doi.org/10.1016/s1474-4422(17)30168-0.

45. Dastgheib S.S., Layegh P., Sadeghi R., et al. The effects of Mozart's music on interictal activity in epileptic patients: systematic review and meta-analysis of the literature. Curr Neurol Neurosci Rep. 2014; 14 (1): 420. https://doi.org/10.1007/s11910-013-0420-x.

46. Lin L.C., Lee M.W., Wei R.C., et al. Mozart K.448 listening decreased seizure recurrence and epileptiform discharges in children with first unprovoked seizures: a randomized controlled study. BMC Complement Altern Med. 2014; 14: 17. https://doi.org/10.1186/1472-6882-14-17.

47. Verrusio W., Ettorre E., Vicenzini E., et al. The Mozart effect: a quantitative EEG study. Conscious Cogn. 2015; 35: 150–5. https://doi.org/10.1016/j.concog.2015.05.005.

48. Coppola G., Operto F.F., Caprio F., et al. Mozart’s music in children with drugrefractory epileptic encephalopathies: comparison of two protocols. Epilepsy Behav. 2018; 8: 100–3. https://doi.org/10.1016/j.yebeh.2017.09.028.

49. D’Alessandro P., Giuglietti M., Baglioni A., et al. Effects of music on seizure frequency in institutionalized subjects with severe/profound intellectual disability and drug-resistant epilepsy. Psychiatr Danub. 2017; 29 (Suppl. 3): 399–404.

50. Tang V., Poon W.S., Kwan P. Mindfulness-based therapy for drugresistant epilepsy: an assessor-blinded randomized trial. Neurology. 2015; 85 (13): 1100–7. https://doi.org/10.1212/wnl.0000000000001967.

51. Mooventhan A., Nivethitha L. Evidence based effects of yoga in neurological disorders. J Clin Neurosci. 2017; 43: 61–7. https://doi.org/10.1016/j.jocn.2017.05.012.

52. Yardi N. Yoga for control of epilepsy. Seizure. 2001; 10 (1): 7–12. https://doi.org/10.1053/seiz.2000.0480.

53. Panebianco M., Sridharan K., Ramaratnam S. Yoga for epilepsy. Cochrane Database Syst Rev. 2017; 10 (10): CD001524. https://doi.org/10.1002/14651858.cd001524.pub3.

54. Sathyaprabha T.N., Satishchandra P., Pradhan C., et al. Modulation of cardiac autonomic balance with adjuvant yoga therapy in patients with refractory epilepsy. Epilepsy Behav. 2008; 12: 245–52. https://doi.org/10.1016/j.yebeh.2007.09.006.

55. Rajesh B., Jayachandran D., Mohandas G., Radhakrishnan K. A pilot study of a yoga meditation protocol for patients with medically refractory epilepsy. J Altern Complement Med. 2006; 12 (4): 367–71. https://doi.org/10.1089/acm.2006.12.367.

56. Lennox W.G., Markham C.H. The sociopsychological treatment of epilepsy. J Am Med Assoc. 1953; 152 (18): 1690–4. https://doi.org/10.1001/jama.1953.03690180012004.

57. Schachter S.C. Epilepsy and art: windows into complexity and comorbidities. Epilepsy Behav. 2016; 57 (Pt. B): 265–9. https://doi.org/10.1016/j.yebeh.2015.12.024.

58. Zolnierek K.B., Dimatteo M.R. Physician communication and patient adherence to treatment: a meta-analysis. Med Care. 2009; 47 (8): 826–34. https://doi.org/10.1097/mlr.0b013e31819a5acc.


For citation:


Maslova N.N., Litvinova A.A., Yuryeva N.V., Kovalev P.S. Compliance in epileptology. How to change the situation for better. Epilepsy and paroxysmal conditions. 2021;13(2):157-167. (In Russ.) https://doi.org/10.17749/2077-8333/epi.par.con.2021.059

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)