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Metabolic disorders in patients with vestibular migraine

https://doi.org/10.17749/2077-8333/epi.par.con.2021.094

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Abstract

Objective: to assess vitamin D deficiency and hyperhomocysteinemia along with psychoemotional status in patients with vestibular migraine.

Material and methods. The neurovestibular examination of 23 patients was performed. All patients were diagnosed with vestibular migraine in accordance with the international criteria. The levels of 25-hydroxyvitamin D and homocysteine were assessed by enzyme-linked immunosorbent assay (ELISA). The effect of dizziness on everyday life was assessed according to the Dizziness Handicap Inventory (DHI). Psychoemotional status was investigated for all patients by using the following scales: Beck depression scale, Spilber–Hanin Scale, Toronto Alexithymia Scale (TAS-26).

Results. The mean level of 25-hydroxyvitamin D was 23±15 ng/ml, homocysteine – 11±3.4 μmol/L. The mean levels of situational and personal anxiety were 48.8±9 and 50.4±10.8, respectively. A correlation analysis revealed a significant positive correlation for Beck's depression parameters and DHI score (Spearman's criterion value 0.64, p=0.0016).

Conclusion. The data obtained evidence about a rather frequent detection of 25-hydroxyvitamin D insufficiency and deficit among patients with vestibular migraine that requires further evaluation, including expanding patients sample and/or comparison with other groups of patients. Of significance was to find an elevated level of anxiety and a correlation between the severity of dizziness (according to DHI score) and the level of depression (based on the Beck Scale).

About the Authors

A. S. Bedenko
Sechenov University
Russian Federation

Anna S. Bedenko – Postgraduate, Chair of Nervous Diseases and Neurosurgery

RSCI SPIN-code: 1533-6140

8 bld. 2 Trubetskaya Str., Moscow 119991



L. M. Antonenko
Sechenov University
Russian Federation

Lyudmila M. Antonenko – Dr. Med. Sc., Professor, Chair of Nervous Diseases and Neurosurgery

Scopus Author ID: 57220812877; RSCI SPIN-code: 2700-0886

8 bld. 2 Trubetskaya Str., Moscow 119991



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Review

For citations:


Bedenko A.S., Antonenko L.M. Metabolic disorders in patients with vestibular migraine. Epilepsy and paroxysmal conditions. 2021;13(4):359-366. (In Russ.) https://doi.org/10.17749/2077-8333/epi.par.con.2021.094

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)