Experience of using EpiTapp application in structural focal epilepsy
https://doi.org/10.17749/2077-8333/epi.par.con.2021.066
Abstract
Background. Non-pharmacological methods of palliative therapy for structural focal epilepsy (SFE) have been extensively investigated. Development of self-care methods based on behavioral psychotherapy and reference bioadaptation is a promising and economically justified approach.
Objective: to present a clinical case of administering EpiTapp application based on the author-proposed wrist tapping method for palliative care in adult SFE.
Material and methods. The author-proposed method of wrist tapping (RF patent No. 2606489 of 01.10.2017) for a smartphone Android OS application was used. Wrist tapping was performed during the period of aura and/or focal seizures (FS) in patients with SFE. Patients used the smartphone application as an element of emergency palliative therapy for SFE outpatient settings.
Results. Patient L., 33 years old, suffering from SFE with frequent FS and bilateral seizures (BS), received duotherapy in the preoperative period. The woman used the EpiTapp application regularly that allowed to reduce FS rate by 65%, as well as prevent BS development without altering the antiepileptic therapy regimen.
Сonclusion. The experience of using the EpiTapp application based on the author-proposed method of wrist tapping has demonstrated that it holds promise for SFE palliative therapy. The proposed technique requires additional research to confirm its effectiveness.
About the Authors
E. A. Narodova
Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
Russian Federation
Ekaterina A. Narodova – MD, PhD, Associate Professor, Chair of Neurological Diseases with Postgraduate Education Course
WoS ResearcherID: AAM-9051-2020; Scopus Author ID: 57203353014; RSCI SPIN-code: 9353-6628
1 Partizan Zheleznyak Str., Krasnoyarsk 660022
N. A. Shnayder
Voino-Yasenetsky Krasnoyarsk State Medical University; Bekhterev National Medical Research Centre for Psychiatry and Neurology
Russian Federation
Russian Federation
Natalia A. Shnayder – Dr. Med. Sc., Professor, Leading Researcher, Center of Collective Usage “Molecular and Cellular Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University; Leading Researcher, Department of Personalized Psychiatry and Neurology, Bekhterev National Medical Research Centre for Psychiatry and Neurology
WoS ResearcherID: M-7084-2014; RSCI SPIN-code: 1952-3043
1 Partizan Zheleznyak Str., Krasnoyarsk 660022
3 Bekhterev Str., Saint Petersburg 192019
V. E. Karnaukhov
Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
Russian Federation
Vladislav E. Karnaukhov – Postgraduate, Chair of Medical Genetics and Clinical Neurophysiology, Institute of Professional Education
1 Partizan Zheleznyak Str., Krasnoyarsk 660022
V. V. Narodova
Voino-Yasenetsky Krasnoyarsk State Medical University
Russian Federation
Russian Federation
Valiria V. Narodova – Dr. Med. Sc., Professor, Chair of Neurological Diseases with Postgraduate Education Course
RSCI SPIN-code: 1431-8530
1 Partizan Zheleznyak Str., Krasnoyarsk 660022
References
1. Cárdenas-Rodríguez N., Carmona-Aparicio L., Pérez-Lozano D.L., et al. Genetic variations associated with pharmacoresistant epilepsy (review). Mol Med Rep. 2020; 21 (4): 1685–701. https://doi.org/10.3892/mmr.2020.10999.
2. Хue-Ping W., Hai-Jiao W., Li-Na Z., et al. Risk factors for drug-resistant epilepsy: a systematic review and meta-analysis. Medicine (Baltimore). 2019; 98 (30): 16402. https://doi.org/10.1097/MD.0000000000016402.
3. Panebianco M., Bresnahan R., Hemming K., Marson A.G. Pregabalin add-on for drug-resistant focal epilepsy. Cochrane Database Syst Rev. 2019; 7 (7): CD005612. https://doi.org/10.1002/14651858.CD005612.pub4.
4. Yoo J.Y., Panov F. Identification and treatment of drug-resistant epilepsy. Continuum (Minneap Minn). 2019; 25 (2): 362–80. https://doi.org/10.1212/CON.0000000000000710.
5. Shnayder N.A., Narodova E.A., Narodova V.V., et al. The role of nondrug treatment methods in the management of epilepsy. In: Isam Jaber Al-Zwaini, Ban Adbul-Hameed Majeed Albadri (Eds.) Epilepsy. Advances in diagnosis and therapy. London: IntechOpen; 2018. https://doi.org/10.5772/intechopen.81912.
6. Gromov S.A., Sivakova N.A. Resolved epilepsy: an updated insight. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2019; 11 (1): 21–6 (in Russ.). https://doi.org/10.17749/2077-8333.2019.11.1.21-26.
7. Wang K.J., Zhang S.H., Yu J.N., et al. A protocol of systematic review and meta-analysis of Mozart’s music for drug-resistant epilepsy. Medicine (Baltimore). 2020; 99 (29): e21090. https://doi.org/10.1097/MD.0000000000021090.
8. Haut S.R., Gursky J.M., Privitera M. Behavioral interventions in epilepsy. Curr Opin Neurol. 2019; 32 (2): 227–36. https://doi.org/10.1097/WCO.0000000000000661.
9. Michaelis R., Tang V., Wagner J.L., et al. Psychological treatments for people with epilepsy. Cochrane Database Syst Rev. 2017; 10 (10): CD012081. https://doi.org/10.1002/14651858.CD012081.pub2.
10. Bedetti C., Principi M., Di Renzo A., et al. The effect of Mozart’s music in severe epilepsy: functional and morphological features. Psychiatr Danub. 2019; 31 (Suppl. 3): 467–74.
11. Voronkova K.V., Klochkov M.N., Koroleva N.Yu., et al. Efficacy and safety of using vagus nerve stimulation in patients with pharmacoresistant epilepsy in the Russian Federation: a multi-center retrospective observational program. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2021; 13 (2): 106–22 (in Russ.). https://doi.org/10.17749/2077-8333/epi.par.con.2021.089.
12. Oleynikova O.M., Sarapulova A.A., Avakyan G.N. Additional options for non-pharmacological treatment of epilepsy. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2019; 11 (1): 8–20 (in Russ.). https://doi.org/10.17749/2077-8333.2019.11.1.8-20.
13. Generalov V.O., Sadykov T.R., Kazakova Yu.V., et al. Musicogenic epilepsy. A review of the literature and a case report. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2018; 10 (1): 25–34 (in Russ.). https://doi.org/10.17749/2077-8333.2018.10.1.025-034.
14. Narodova E.A., Shnayder N.A., Karnaukhov V.E., et al. Influence of wrist tapping on alpha rhythm synchronization in patients with juvenile myoclonic epilepsy. Int J Biomed. 2020; 10 (4): 347–51. https://doi.org/10.21103/Article10(4)_OA3.
15. Narodova E.A., Shnayder N.A., Karnaukhov V.E., et al. Study of the influence of wrist tapping on alpha-rhythm synchronization in adults. Archiv Euromedica. 2020; 10 (4): 118–23. https://doi.org/10.35630/2199-885X/2020/10/4.28.
16. Vollmar C., O’Muircheartaigh J., Barker G.J., et al. Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study. Brain. 2011; 134 (6): 1710–9. https://doi.org/10.1093/brain/awr098.
17. Caciagli L., Wandschneider B., Xiao F., et al. Abnormal hippocampal structure and function in juvenile myoclonic epilepsy and unaffected siblings. Brain. 2019; 142 (9): 2670–87. https://doi.org/10.1093/brain/awz215.
18. Narodova E.A., Rudnev V.A., Shnayder N.A., et al. Parameters of the wrist tapping using a modification of the Original Method (Method of exogenous rhythmic stimulation influence on an individual human rhythm). Int J Biomed. 2018; 8 (2): 155–8. https://doi.org/10.21103/Article8(2)_OA10.
19. Narodova E.A., Shnayder N.A., Narodova V.V., et al. The effect of anxiety on the parameters of carpal tapping in patients with post-stroke epilepsy. Epilepsia i paroksizmalʹnye sostoania / Epilepsy and Paroxysmal Conditions. 2020; 12 (1): 26–35. https://doi.org/10.17749/2077-8333.2020.12.1.26-35.
20. Narodova E.A., Narodova V.V., Petrov K.V., et al. Efficiency and safety of the author's method of wrist tapping as a personalized method of emergency self-help in focal epilepsy. Personalized Psychiatry and Neurology. 2021; 1 (2): 106–10.
21. Engel J. Jr., McDermott M.P., Wiebe S., et al. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012; 307 (9): 922–30. https://doi.org/10.1001/jama.2012.220.
Review
For citations:
Narodova E.A., Shnayder N.A., Karnaukhov V.E., Narodova V.V. Experience of using EpiTapp application in structural focal epilepsy. Epilepsy and paroxysmal conditions. 2021;13(4):367-376. (In Russ.) https://doi.org/10.17749/2077-8333/epi.par.con.2021.066
Views:
856
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Email this article 
