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Complex of acquired disturbances of cognitive functions in children associated with continuous epileptiform activity on the EEG is a serious problem. Quite often the EEG patterns in epileptic encephalopathies of childhood such as Landau-Kleffner, pseudo-Lennox syndromes, autistic epileptiform regression etc. are represented by the so-called «benign focal epileptiform discharges of childhood» (BEDOC, BFEDC, BEDC). Epileptiform discharges are characterized by high index and diffuse spreading nature, especially during slow-wave sleep, forming the pattern of ESES. In the treatment of epileptic encephalopathies the following AEDs are applied in monotherapy or rational combined therapy: valproates, ethosuximide, levetiracetam, sultiame and benzodiazepines.

About the Author

A. A. Kholin
Pirogov Russian National Research Medical University of the Russian Federation Ministry of Heath
Russian Federation

DM, Professor of Neurology, Neurosurgery and Medical Genetics Department of Pediatric Faculty, Pirogov Russian National Research Medical University. Address: ul. Ostrovityanova, 1, Moscow, Russia, 117997. Tel.: +7(916)372-66-79


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Supplementary files

For citation: Kholin A.A. EPILEPTIC ENCEPHALOPTHIES WITH ELECTRICAL STATUS EPILEPTICUS SLOW SLEEP (ESES). Epilepsia and paroxyzmal conditions. 2016;8(1):62-65. https://doi.org/10.17749/2077-8333.2016.8.1.062-065

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