Клинико-эпидемиологические исследования лития как фактора профилактики импульсивного поведения, суицида, стрессовых расстройств указывают на необходимость восполнения эссенциальных микродоз лития при эпилепсии

Исследования, проводимые в течение последних 40 лет, указывают на эссенциальность (жизненную необходимость) ультрамикроэлемента лития. Одним из критериев эссенциальности микроэлементов является наличие результатов клинико-эпидемиологических исследований,  подтверждающих негативные последствия недостаточного потребления лития в масштабе популяций. Достаточная обеспеченность литием оказывает нейропротекторное,  ноотропное и нормотимическое действие. Более низкие уровни лития в крови  ассоциированы с повышенным риском варикоза, расстройств сна, экстрапирамидных нарушений и бокового  амиотрофического склероза. Обширная клинико-эпидемиологическая база  информации  демонстрирует четкую взаимосвязь более низких уровней иона лития в питьевой воде с повышенным риском самоубийств,  психотических стрессовых расстройств, болезней зависимости, тяжкой преступности и импульсивного поведения (которое является фактором  риска и суицидальности, и агрессивности,  приводящей к тяжким преступлениям). Прием препаратов лития способствует торможению деменции (как сосудистой,  так и нейродегенеративной природы) и других поведенческих нарушений, связанных со старением, включая общий риск опухолевых заболеваний, переломов,  переедания и булимии. Использование препаратов на основе солей лития и повышение обеспеченности литием через питьевую воду позволяет снизить судорожную готовность, импульсивность поведения, а также риск самоубийств,  тревожности и депрессии у пациентов с эпилепсией. В настоящей работе представлены результаты систематизации научной литературы по данному вопросу.

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