EXPERIENCE OF PROLONGED VALPROATE USE IN ADULT PATIENTS WITH FOCAL FORMS OF EPILEPSY (RESULTS OF OBSERVATION HELD IN OUT-PATIENT CLINICS OF MOSCOW)
Abstract
Results of Depakine Chronosphere use in Moscow city out-patient clinics are demonstrated in the article. 48 patients with focal forms of epilepsy (cryptogenic and symptomatic) were examined: 32 men and 16 women in age of 16 - 59 years with different duration of disease and different types of seizures. Depakine Chronosphere was indicated to patients who were already taking antiepileptic drugs in monotherapy with efficacy of 50% and more, and also to patients with drug remission, but with side effects, requiring changes of current indications. Results of the observation demonstrated high efficacy of Depakine Chronosphere in adult patients with different forms of focal epilepsy in monotherapy and also its use possibility in case of noneffective or poor tolerability of other valproates and carbamazepine.
About the Authors
S. G. Burd
Chair of neurology and neurosurgery GBOU VPO Russian National Investigational Medical University named after N.I. Pirogov, Ministry of Health and Social Development of the Russian Federation (Moscow)
Russian Federation
Russian Federation
A. V. Lebedeva
Chair of neurology and neurosurgery GBOU VPO Russian National Investigational Medical University named after N.I. Pirogov, Ministry of Health and Social Development of the Russian Federation (Moscow)
Russian Federation
Russian Federation
I. Yu. Artyomova
Moscow City Polyclinics
Russian Federation
Russian Federation
O. L. Badalyan
Moscow City Polyclinics
Russian Federation
Russian Federation
M. A. Bogomazova
Moscow City Polyclinics
Russian Federation
Russian Federation
I. I. Zhuravlyeva
Moscow City Polyclinics
Russian Federation
Russian Federation
A. M. Ismailov
Moscow City Polyclinics
Russian Federation
Russian Federation
E. G. Komelkova
Moscow City Polyclinics
Russian Federation
Russian Federation
L. N. Lesinker
Moscow City Polyclinics
Russian Federation
Russian Federation
Yu. I. Logvinov
Moscow City Polyclinics
Russian Federation
Russian Federation
O. V. Otcheskaya
Moscow City Polyclinics
Russian Federation
Russian Federation
S. V. Petrov
Moscow City Polyclinics
Russian Federation
Russian Federation
Yu. V. Solomatin
Moscow City Polyclinics
Russian Federation
Russian Federation
A. M. Teplysheva
Moscow City Polyclinics
Russian Federation
Russian Federation
T. N. Vdovichenko
Moscow City Polyclinics
Russian Federation
Russian Federation
E. A. Khromykh
Moscow City Polyclinics
Russian Federation
Russian Federation
A. S. Chukanova
Moscow City Polyclinics
Russian Federation
Russian Federation
A. N. Boiko
Chair of neurology and neurosurgery GBOU VPO Russian National Investigational Medical University named after N.I. Pirogov, Ministry of Health and Social Development of the Russian Federation (Moscow)
Russian Federation
Russian Federation
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Review
For citations:
Burd S.G., Lebedeva A.V., Artyomova I.Yu., Badalyan O.L., Bogomazova M.A., Zhuravlyeva I.I., Ismailov A.M., Komelkova E.G., Lesinker L.N., Logvinov Yu.I., Otcheskaya O.V., Petrov S.V., Solomatin Yu.V., Teplysheva A.M., Vdovichenko T.N., Khromykh E.A., Chukanova A.S., Boiko A.N. EXPERIENCE OF PROLONGED VALPROATE USE IN ADULT PATIENTS WITH FOCAL FORMS OF EPILEPSY (RESULTS OF OBSERVATION HELD IN OUT-PATIENT CLINICS OF MOSCOW). Epilepsy and paroxysmal conditions. 2012;4(2):56-66. (In Russ.)
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