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EXPERIENCE WITH USE OF CHRONIC NEUROSTIMULATION OF VAGUS NERVE IN TREATMENT OF PHARMACORESISTANT EPILEPSY

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Abstract

This article presents the results of vagus nerve chronic stimulation in 11 patients with pharmacoresistant epilepsy who are not on the wait-list for direct surgical treatment. During the first three months of nervestimulation 27,3% of patients demonstrated a 50% seizure-frequency reduction as compared to baseline, with no surgical or infectious complications. 27,3% Of patients demonstrated transient side effects of nerve stimulation, such as dysphonia, trouble breathing or throat paresthesias.

About the Authors

А. А. Sufianov
Federal state-funded institution «Federal center of neurosurgery», Tumen
Russian Federation


А. S. Orlov
Federal state-funded institution «Federal center of neurosurgery», Tumen
Russian Federation


Е. I. Matveev
Federal state-funded institution «Federal center of neurosurgery», Tumen
Russian Federation


D. I. Lebedeva
State autonomous healthcare institution of Tumen region, Regional clinical hospital of medical rehabilitation, Tumen
Russian Federation


References

1. Amar A.P., Apuzzo Michael L.J., Liu Charles Y. Vagus nerve stimulation therapy after failed cranial surgery for intractable epilepsy: results from the vagus nerve stimulation therapy patient outcome registry. Neurosurgery. 2004, 55:1086-1093.

2. Annegers J.F. et al. Epilepsy, vagal nerve stimulation by the NCP system, mortality, and sudden, unexpected, unexplained death. Epilepsia. 1998; 39: 206-212.

3. Binnie C.D. Vagus nerve stimulation for epilepsy: a review. Seizure. 2000; 9 (3): 161-169.

4. Brodie M.L., Kwan P. Neurology. 2002; 58 (suppl. 5): 2-8.

5. Kwan P., Brodie M.J.. Early identification of refractory epilepsy. New England Journal of Medicine. 2002; 342 (5): 314-319.

6. Lhatoo S.D. et al. Sudden unexpected death in epilepsy. Postgrad. Med. J. 1999; 75: 706- 709.

7. Meador K.J. Neurology. 2002; 58 (suppl 5): 21-26.

8. Mohanraj R., Brodie M.J. Diagnosing intractable epilepsy: response to sequential treatment schedules. Eur. J. Neurol. 2006; 13: 277-282.

9. National Institutes of Health Consensus Conference: Surgery for epilepsy. JAMA 264. 1990; 729-733.

10. Renfroe J.B., Whelees J.W. Earlier use of an adjunctive vagus nerve stimulation therapy for refractory epilepsy. Neurology. 2002; Sept., 59 (4).

11. Shahwan A., Bailey C., Maxiner W., Harvey A.S. Vagus nerve stimulation for refractory epilepsy in children: More to VNS then seizure frequency reduction. Epilepsia. 2009; Sept., 50(5): 1220-1228.

12. The Vagus Nerve Stimulation Study Group: A randomized controlled trial of chronic vagus nerve stimulation for treatment of medically intractable seizures. Neurology. 1995; 45: 224-230.

13. Van Ness P.C. Therapy for the epilepsies. Arch. Neurol. 2002; 59: 732-735.

14. Wheless J.W., Maggio V. Vagus nerve stimulation therapy in patients younger than 18 years. Neurology. 2002; 59 (4): 21-25.


For citation:


Sufianov А.А., Orlov А.S., Matveev Е.I., Lebedeva D.I. EXPERIENCE WITH USE OF CHRONIC NEUROSTIMULATION OF VAGUS NERVE IN TREATMENT OF PHARMACORESISTANT EPILEPSY. Epilepsy and paroxysmal conditions. 2012;4(3):48-49. (In Russ.)

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)