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EXPERIENCE OF TREATMENT WITH GENERIC LAMOTRIDJIN IN DIFFERENT FORMS OF EPILEPSY (The results of focus observation in out-patient clinics network of Moscow city public healthcare services)

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Abstract

Focused observational study on efficacy, tolerability and quality of life in adult patients with different forms of epilepsy taking combined therapy with lamotrigine (Sazar). 32 patients (19 men and 13 women), 23-79 years old with focal forms (cryptogenic and symptomatic) epilepsy with different disease duration and presence of of different type and etiology seizures were enrolled into the study. Patients having been taken various antiepileptic drugs in monotherapy with different efficacy degree were observed. Patients sample included 20 patients, receiving valproic acid in various dosages and 12 patients, receiving topiramate. Sazar was added as a second drug with initial dosage of 25 mg daily. Results of focused observation allow us to make conclusion of possible expedience of Sazar indication, especially in patients in whom therapy with valproic acid is less effective.

About the Authors

O. L. Badalyan
City polyclinics, Moscow
Russian Federation


M. A. Bogomazova
City polyclinics, Moscow
Russian Federation


I. I. Zhuravleva
City polyclinics, Moscow
Russian Federation


A. M. Ismailov
City polyclinics, Moscow
Russian Federation


. .
City polyclinics, Moscow
Russian Federation


E. G. Komelkova
City polyclinics, Moscow
Russian Federation


L. N. Lesinker
City polyclinics, Moscow
Russian Federation


Yu. I. Logvinov
City polyclinics, Moscow
Russian Federation


O. V. Otcheskaya
City polyclinics, Moscow
Russian Federation


S. V. Petrov
City polyclinics, Moscow
Russian Federation


Yu. V. Solomatin
City polyclinics, Moscow
Russian Federation


A. M. Teplysheva
City polyclinics, Moscow
Russian Federation


T. N. Udovuchenko
City polyclinics, Moscow
Russian Federation


A. E. Khromykh
City polyclinics, Moscow
Russian Federation


A. S. Chukanova
City polyclinics, Moscow
Russian Federation


A. V. Lebedeva
City polyclinics, Moscow
Russian Federation


S. G. Burd
GBOU VPO RNIMU named after N.I. Pirogov, Moscow
Russian Federation


A. N. Boiko
GBOU VPO RNIMU named after N.I. Pirogov, Moscow


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For citation:


Badalyan O.L., Bogomazova M.A., Zhuravleva I.I., Ismailov A.M., . .., Komelkova E.G., Lesinker L.N., Logvinov Y.I., Otcheskaya O.V., Petrov S.V., Solomatin Y.V., Teplysheva A.M., Udovuchenko T.N., Khromykh A.E., Chukanova A.S., Lebedeva A.V., Burd S.G., Boiko A.N. EXPERIENCE OF TREATMENT WITH GENERIC LAMOTRIDJIN IN DIFFERENT FORMS OF EPILEPSY (The results of focus observation in out-patient clinics network of Moscow city public healthcare services). Epilepsy and paroxysmal conditions. 2012;4(4):40-48. (In Russ.)

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)