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Neurophysiological parameters and the tone of the autonomic nervous system in patients with migraine and epilepsy

https://doi.org/10.17749/2077-8333.2018.10.2.026-034

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Abstract

Aim: to study the bioelectric activity of the brain in relation to changes in the tone of the autonomic nervous system as assessed by heart rate variability (HRV) and evoked skin  sympathetic potentials (ESSP) in patients with migraine and epilepsy.

Materials and methods. We studied patients with epileptic foci in the left (group 1) or right (group 2) hemisphere with migraine attacks followed by epileptic seizures. We used EEG recording  and EEG mapping programs and also determined HRV and ESSP.

Results. We found that the subjects in group 1 had the normothymic and parasympathetic types  of heart rate control, and the subjects in group 2 tended toward the sympathetic type of heart rate  regulation. The spectral correlation EEG data indicated that the epileptiform activity in group  1 was more generalized than in group 2, which pointed to a more pronounced epileptogenesis in  group 1. In this group, all pain scores were higher than those in group 2. In group 2 though, depression, anxiety, and emotional disorders were more pronounced than in group 1.

Conclusion. The findings can be explained by a closer connection between the right hemisphere and the limbic system. This, in our view, underlies the more pronounced changes in the tone of the  autonomic nervous system as assessed by the HRV and ESSP in patients with the right hemisphere epileptic activity and migraine attacks.

About the Authors

N. D. Sorokina
A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Healthcare of the Russian Federation
Russian Federation

20-1 Delegatskaya str., Moscow 127473, Russia

MD, PhD (Biology), Professor at the Department of Normal Physiology and Medical Physics, Faculty  of Medicine, A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of  Healthcare of the Russian Federation. Tel.: +7 (495) 959-16-58



G. V. Selitsky
A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Healthcare of the Russian Federation
Russian Federation

20-1 Delegatskaya str., Moscow 127473, Russia

MD, PhD (Biology), Honored Doctor of the Russian Federation, Professor at the Department of  Nervous Diseases, Faculty of Medicine, A. I. Evdokimov Moscow State University of Medicine and  Dentistry, the Ministry of Healthcare of the Russian Federation. Tel.: +7 (495) 261-28-43



A. V. Tsagashek
A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Healthcare of the Russian Federation
Russian Federation

20-1 Delegatskaya str., Moscow 127473, Russia

MD, Research Fellow at the Department of Nervous Diseases, Faculty of Medicine, A. I. Evdokimov  Moscow State University of Medicine and Dentistry, the Ministry of Healthcare of the Russian  Federation; Neurologist at Clinical Hospital No.50 in the city of Moscow



A. S. Zherdeva
A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Healthcare of the Russian Federation
Russian Federation

20-1 Delegatskaya str., Moscow 127473, Russia

Lab Assistant at the Department of Normal Physiology and Medical Physics, Faculty of Medicine, A. I.  Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Healthcare of the  Russian Federation; Neurologist at Clinical Hospital No.50 in the city of Moscow



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For citation:


Sorokina N.D., Selitsky G.V., Tsagashek A.V., Zherdeva A.S. Neurophysiological parameters and the tone of the autonomic nervous system in patients with migraine and epilepsy. Epilepsy and paroxysmal conditions. 2018;10(2):26-34. (In Russ.) https://doi.org/10.17749/2077-8333.2018.10.2.026-034

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)