Today’s choice of antiepileptic therapy: stages and recommendations
https://doi.org/10.17749/2077-8333.2018.10.2.074-081
Abstract
At present, treatment recommendations are developed considering the principles of evidence-based medicine. General practitioners (GP) are offered a choice of different medications with the known characteristics of efficacy and tolerance. For a GP, the right choice of the optimal drug from the proposed list may become a problem. Therefore, it is important not only to provide complete information on all treatment options for a patient with epilepsy, but also discuss a scheme of the proposed therapy (“key”) so to guide a GP through the treatment options and assess the possibility of alternative treatment strategies. Contrary to the trial and error method, when the drug efficacy and safety is assessed during the treatment, the proposed optimized approach allows for achieving a maximal therapeutic effect in patients with epilepsy.
About the Authors
K. V. Voronkova
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Central clinical hospital of the Russian Academy of Sciences
Russian Federation
Russian Federation
1 Ostrovityanova Str., Moscow 117997, Russia
10 Fotievoi Str., Moscow 119333, Russia
MD, Professor of Neurology, N. I. Pirogov Russian National Research Medical University
A. E. Nikitin
Central clinical hospital of the Russian Academy of Sciences
Russian Federation
Russian Federation
10 Fotievoi Str., Moscow 119333, Russia
MD, Professor, Chief Physician, Central Clinical Hospital of the Russian Academy of Sciences
I. G. Rudakova
Moscow Regional Research and Clinical Institute (MONIKI)
Russian Federation
Russian Federation
61/2 Shchepkina Str., 129110 Moscow, Russia
MD, Professor, Moscow Regional Research and Clinical Institute
P. N. Vlasov
A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
20-1 Delegatskaya str., Moscow 127473, Russia
MD, Professor of Neurology, Faculty of Medicine, A. I. Evdokimov Moscow State University of Medicine and Dentistry
S. G. Burd
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
1 Ostrovityanova Str., Moscow 117997, Russia
MD, Professor, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics, N. I. Pirogov Russian National Research Medical University
A. V. Lebedeva
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Scientific Research Institute of Healthcare and Medical Management of the Moscow City Health Department
Russian Federation
Russian Federation
1 Ostrovityanova Str., Moscow 117997, Russia
9 Sharikopodshipnikovskaya, Moscow 115088, Russia
MD, Professor, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine, N. I. Pirogov Russian National Research Medical University; Scientific Research Institute of Healthcare and Medical Management of the Moscow City Health Department
G. N. Avakyan
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
1 Ostrovityanova Str., Moscow 117997, Russia
MD, Honored Scientist of Russia, Professor, Department of Neurology, Neurosurgery and Medical Genetics, N. I. Pirogov Russian National Research Medical University
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Review
For citations:
Voronkova K.V., Nikitin A.E., Rudakova I.G., Vlasov P.N., Burd S.G., Lebedeva A.V., Avakyan G.N. Today’s choice of antiepileptic therapy: stages and recommendations. Epilepsy and paroxysmal conditions. 2018;10(2):74-81. (In Russ.) https://doi.org/10.17749/2077-8333.2018.10.2.074-081
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