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Epilepsy and paroxysmal conditions

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Today’s choice of antiepileptic therapy: stages and recommendations

https://doi.org/10.17749/2077-8333.2018.10.2.074-081

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Abstract

At present, treatment recommendations are developed considering the principles of evidence-based medicine. General practitioners (GP) are offered a choice of different medications with the known  characteristics of efficacy and tolerance. For a GP, the right choice of the optimal drug from the  proposed list may become a problem. Therefore, it is important not only to provide complete  information on all treatment options for a patient with epilepsy, but also discuss a scheme of the  proposed therapy (“key”) so to guide a GP through the treatment options and assess the possibility of  alternative treatment strategies. Contrary to the trial and error method, when the drug efficacy and  safety is assessed during the treatment, the proposed optimized approach allows for achieving a maximal therapeutic effect in patients with epilepsy.

About the Authors

K. V. Voronkova
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia Central clinical hospital of the Russian Academy of Sciences
Russian Federation

1 Ostrovityanova Str., Moscow 117997, Russia

10 Fotievoi Str., Moscow 119333, Russia

MD, Professor of Neurology, N. I. Pirogov Russian National Research Medical University



A. E. Nikitin
Central clinical hospital of the Russian Academy of Sciences
Russian Federation

10 Fotievoi Str., Moscow 119333, Russia

MD, Professor, Chief Physician, Central Clinical Hospital of the Russian Academy of Sciences



I. G. Rudakova
Moscow Regional Research and Clinical Institute (MONIKI)
Russian Federation

61/2 Shchepkina Str., 129110 Moscow, Russia

MD, Professor, Moscow Regional Research and Clinical Institute



P. N. Vlasov
A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of the Russian Federation
Russian Federation

20-1 Delegatskaya str., Moscow 127473, Russia

MD, Professor of Neurology, Faculty of Medicine, A. I. Evdokimov Moscow State University of Medicine and Dentistry



S. G. Burd
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

1 Ostrovityanova Str., Moscow 117997, Russia

MD, Professor, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Pediatrics, N. I. Pirogov Russian National Research Medical University



A. V. Lebedeva
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia Scientific Research Institute of Healthcare and Medical Management of the Moscow City Health Department
Russian Federation

1 Ostrovityanova Str., Moscow 117997, Russia

9 Sharikopodshipnikovskaya, Moscow 115088, Russia

MD, Professor, Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine, N. I. Pirogov Russian National Research Medical University; Scientific Research  Institute of Healthcare and Medical Management of the Moscow City Health Department



G. N. Avakyan
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation

1 Ostrovityanova Str., Moscow 117997, Russia

MD, Honored Scientist of Russia, Professor, Department of Neurology, Neurosurgery and Medical  Genetics, N. I. Pirogov Russian National Research Medical University



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For citation:


Voronkova K.V., Nikitin A.E., Rudakova I.G., Vlasov P.N., Burd S.G., Lebedeva A.V., Avakyan G.N. Today’s choice of antiepileptic therapy: stages and recommendations. Epilepsy and paroxysmal conditions. 2018;10(2):74-81. (In Russ.) https://doi.org/10.17749/2077-8333.2018.10.2.074-081

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)