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Use of autologous mesenchymal stem cells in the combined treatment of symptomatic epilepsy

https://doi.org/10.17749/2077-8333.2019.11.2.176-186

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Abstract

This article presents the results of the clinical application of the method of transplantation of autologous bone marrow stem cells in the treatment of a patient with pharmacoresistant epilepsy, the effectiveness of combination therapy, including antiepileptic drugs and autologous bone marrow stem cells and assess the feasibility, tolerability of this kind of local treatment. The encouraging results of the effectiveness of the proposed method of treatment of pharmacoresistant epilepsy on the clinical case of one patient have been obtained, which requires further study of the clinical application of the AMSC CM transplantation method on a more significant number of clinical cases in larger clinical trials.

About the Authors

F. P. Khlebokazov
Republican Scientific and Practical Center for Mental Health
Belarus

FedorP. Khlebokazov- MD, PhD, Leading Researcher.

Dolginovsky tract, 152, Minsk 220053



T. V. Dokukina
Republican Scientific and Practical Center for Mental Health
Belarus

Tat’yana V. Dokukina - MD, PhD, Deputy Director for Research.

Dolginovsky tract, 152, Minsk 220053



N. Yu. Paramonova
N.N. Alexandrov National Cancer Center of Belarus
Belarus

Natal’ya Yu. Paramonova - MD, Expert in Radionuclide Diagnostics, Practical Center of Oncology and Medical Radiology.

Agro-town Lesnoy, Minsk region 223040



S. I. Gotto
N.N. Alexandrov National Cancer Center of Belarus
Belarus

Svetlana I. Gotto - MD, Head of the PET and CT Unit, Expert in Radionuclide Diagnostics, Practical Center of Oncology and Medical Radiology.

Agro-town Lesnoy, Minsk region 223040



I. I. Khvostova
Republican Scientific and Practical Center for Mental Health
Belarus

Irina I. Khvostova - MD, PhD, Deputy Director for Medicine (Psychiatry).

Dolginovsky tract, 152, Minsk 220053



N. N. Misyuk
Republican Scientific and Practical Center for Mental Health
Belarus

Nikolai N. Misyuk- MD, PhD, Chief Researcher.

Dolginovsky tract, 152, Minsk 220053



A. I. Martynenko
Republican Scientific and Practical Center for Mental Health
Belarus

Aleksandr I. Martynenko - MD, Psychiatrist & Psychologist.

Dolginovsky tract, 152, Minsk 220053


Е. L. Slobina
Russian Scientific Center of RoentgenoRadiology
Russian Federation

Elena L. Slobina - MD, PhD, Senior Researcher.

86 Profsoyuznaya Str., Moscow 117997


I. V. Shamruk
Republican Scientific and Practical Center for Mental Health
Belarus

Irina V. Shamruk- MD, Neurologist.

Dolginovsky tract, 152, Minsk 220053



References

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For citation:


Khlebokazov F.P., Dokukina T.V., Paramonova N.Y., Gotto S.I., Khvostova I.I., Misyuk N.N., Martynenko A.I., Slobina Е.L., Shamruk I.V. Use of autologous mesenchymal stem cells in the combined treatment of symptomatic epilepsy. Epilepsy and paroxysmal conditions. 2019;11(2):176-186. (In Russ.) https://doi.org/10.17749/2077-8333.2019.11.2.176-186

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)