Use of autologous mesenchymal stem cells in the combined treatment of symptomatic epilepsy
F. P. Khlebokazov,
T. V. Dokukina,
N. Yu. Paramonova,
S. I. Gotto,
I. I. Khvostova,
N. N. Misyuk,
A. I. Martynenko, 
Е. L. Slobina,
I. V. Shamruk
Е. L. Slobina,
I. V. Shamruk https://doi.org/10.17749/2077-8333.2019.11.2.176-186
Abstract
This article presents the results of the clinical application of the method of transplantation of autologous bone marrow stem cells in the treatment of a patient with pharmacoresistant epilepsy, the effectiveness of combination therapy, including antiepileptic drugs and autologous bone marrow stem cells and assess the feasibility, tolerability of this kind of local treatment. The encouraging results of the effectiveness of the proposed method of treatment of pharmacoresistant epilepsy on the clinical case of one patient have been obtained, which requires further study of the clinical application of the AMSC CM transplantation method on a more significant number of clinical cases in larger clinical trials.
About the Authors
F. P. Khlebokazov
Republican Scientific and Practical Center for Mental Health
Belarus
Belarus
FedorP. Khlebokazov- MD, PhD, Leading Researcher.
Dolginovsky tract, 152, Minsk 220053
T. V. Dokukina
Republican Scientific and Practical Center for Mental Health
Belarus
Belarus
Tat’yana V. Dokukina - MD, PhD, Deputy Director for Research.
Dolginovsky tract, 152, Minsk 220053
N. Yu. Paramonova
N.N. Alexandrov National Cancer Center of Belarus
Belarus
Belarus
Natal’ya Yu. Paramonova - MD, Expert in Radionuclide Diagnostics, Practical Center of Oncology and Medical Radiology.
Agro-town Lesnoy, Minsk region 223040
S. I. Gotto
N.N. Alexandrov National Cancer Center of Belarus
Belarus
Belarus
Svetlana I. Gotto - MD, Head of the PET and CT Unit, Expert in Radionuclide Diagnostics, Practical Center of Oncology and Medical Radiology.
Agro-town Lesnoy, Minsk region 223040
I. I. Khvostova
Republican Scientific and Practical Center for Mental Health
Belarus
Belarus
Irina I. Khvostova - MD, PhD, Deputy Director for Medicine (Psychiatry).
Dolginovsky tract, 152, Minsk 220053
N. N. Misyuk
Republican Scientific and Practical Center for Mental Health
Belarus
Belarus
Nikolai N. Misyuk- MD, PhD, Chief Researcher.
Dolginovsky tract, 152, Minsk 220053
A. I. Martynenko
Republican Scientific and Practical Center for Mental Health
Belarus
Belarus
Aleksandr I. Martynenko - MD, Psychiatrist & Psychologist.
Dolginovsky tract, 152, Minsk 220053Е. L. Slobina
Russian Scientific Center of RoentgenoRadiology
Russian Federation
Russian Federation
Elena L. Slobina - MD, PhD, Senior Researcher.
86 Profsoyuznaya Str., Moscow 117997I. V. Shamruk
Republican Scientific and Practical Center for Mental Health
Belarus
Belarus
Irina V. Shamruk- MD, Neurologist.
Dolginovsky tract, 152, Minsk 220053
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Review
For citations:
Khlebokazov F.P., Dokukina T.V., Paramonova N.Yu., Gotto S.I., Khvostova I.I., Misyuk N.N., Martynenko A.I., Slobina Е.L., Shamruk I.V. Use of autologous mesenchymal stem cells in the combined treatment of symptomatic epilepsy. Epilepsy and paroxysmal conditions. 2019;11(2):176-186. (In Russ.) https://doi.org/10.17749/2077-8333.2019.11.2.176-186
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