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THE BASIC REGULATOR OF THE CIRCADIAN SYSTEM IN EPILEPSY

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Abstract

Abstract: there were significant increase in the values of the evening melatonin excretion in the spring of the year compared to the autumn. In patients with epilepsy, nocturnal seizures, nocturnal melatonin excretion two times lower than in patients with daytime seizures. In the spring, the evening excretion increased COMT 6; concentration morning urinary 6-COMT higher with anticonvulsant therapy with valproic acid compared with carbamazepine.

About the Authors

G. N. Avakyan
Pirogov Russian National Research Medical University, Moscow
Russian Federation


O. M. Oleinikova
Pirogov Russian National Research Medical University, Moscow
Russian Federation


E. N. Kareva
Pirogov Russian National Research Medical University, Moscow
Russian Federation


M. A. Bogomazova
Pirogov Russian National Research Medical University, Moscow
Russian Federation


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For citation:


Avakyan G.N., Oleinikova O.M., Kareva E.N., Bogomazova M.A. THE BASIC REGULATOR OF THE CIRCADIAN SYSTEM IN EPILEPSY. Epilepsy and paroxysmal conditions. 2014;6(4):67-71. (In Russ.)

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ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)