HYPOMELANOSIS OF ITO WITH EPILEPSY: TWO CASES IN CLINICAL PRACTICE
Abstract
Hypomelanosis of Ito (HI) is rare genetic disorder of the phakomatoses group. Authors represent literature review on the history of the HI description, etiology, clinical features, diagnosis, and approaches to therapy. Special attention is description is characteristics of epilepsy and EEG to HI. We also discuss different approaches to the treatment of epilepsy. So HI is rare disease the authors carried out a comparative analysis of the observed two patients with HI and epilepsy with literature data.
About the Authors
M. B. Mironov
Institute of Child Neurology and Epilepsy them. St. Luke, Moscow
Russian Federation
Russian Federation
N. Yu. Borovikova
Institute of Child Neurology and Epilepsy them. St. Luke, Moscow
Russian Federation
Russian Federation
K. S. Borovikov
Institute of Child Neurology and Epilepsy them. St. Luke, Moscow
Russian Federation
Russian Federation
K. Yu. Mukhin
Institute of Child Neurology and Epilepsy them. St. Luke, Moscow
Russian Federation
Russian Federation
References
1. Мухин К.Ю., Боровиков К.С., Кузина Н.Ю., Петрухин А.С., Гаман О.В., Шпрехер Б.Л. Гипомеланоз Ито – редкий случай из практики невролога. Русский журнал детской неврологии. 2006. Т. 1(1). С. 38–41.
2. Мухин К.Ю. Гипомеланоз Ито. В книге под ред. К.Ю. Мухина, А.С. Петрухина, А.А. Холина. Эпилептические энцефалопатии и схожие синдромы у детей. Москва: АртСервис Лтд. 2011.С. 427–676.
3. Темин П.А., Казанцева Л.З. Наследственные нарушения нервно-психического развития детей. Москва: Медицина. 2001. С. 312–315.
4. Aicardi J. Diseases of the nervous system in childhood, 2-nd edition. Cambridge Mac Keith Press. 1998. Р. 145–146.
5. Cross H. Neurocutaneous syndromes and epilepsy – issues in diagnosis and management. Epilepsia. 2005. V. 46. Suppl.10. P. 17–23.
6. Fujino O., Hashimoto K., Fujita T. с соавт. Clinico-neuropathological study of incontinentia pigmenti achromians – an autopsy case. Brain Dev. 1995. V. 17. Р. 425–427.
7. Ito M. Studies of melanin XI. Incontinentia pigmenti achromians, singular case of naevus dipigmentosis systematicus bilateralis. Tohoku J. Exp. Med. 1952. V. 55. P. 57–59.
8. Maria B.L., Menkes J.H. Neurocutaneous syndromes. In: Child Neurology – 7th edition. Eds.: J.H. Menkes, H.B.Sarnat, B.L.Maria. – Lippincott Williams Wilkins. 2005. P. 822–823.
9. Ogino T., Hata H., Minakuchi E. с соавт. Neurophysiologic dysfunction in hypomelanosis Ito: EEG and evoked potential studies. Brain Dev. – 1994. V. 16. P. 407– 412.
10. Pascual-Castroviejo I., Roche C., MartinezBermejo A. с соавт. Hypomelanosis of Ito. A study of 76 infantile cases. Brain Dev. 1998. V. 20(1). P. 36–43.
11. Placantonakis D., Ney G., Edgar M., Souweidane M., Hosain S., Schwartz T. Neurosurgical management of medically intractable epilepsy associated with hypomelanosis Ito. Epilepsia. 2005. V. 46(2). P. 329–331.
12. Rubin M. Incontinentia pigmenti achromians. Multiple cases within a family. Arch. Dermatol. 1972. V. 105(3). Р. 424–425.
For citation:
Mironov M.B., Borovikova N.Yu., Borovikov K.S., Mukhin K.Yu. HYPOMELANOSIS OF ITO WITH EPILEPSY: TWO CASES IN CLINICAL PRACTICE. Epilepsy and paroxysmal conditions. 2012;4(1):8-12. (In Russ.)
Views: 390
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Email this article 
