Vol 6, No 3 (2014)
ORIGINAL ARTICLES
13-19 578
Abstract
Abstract: The article content results of estimation of Blink Reflex and evoked brain potentials (cognitive and visual) parameters changes on epilepsy patients, which treated by anticonvulsants and repetitive transcranial magnetic stimulation course (rTMS). Data of Blink Reflex parameters on dependence from epileptic process activity were given. Received data define some aspects of epilepsy pathogenesis and widen conception about long-lasting processes of brain reaction after short rTMS course.
20-29 4761
Abstract
Abstract: gelastic seizures are focal epileptic seizures that involve sudden outbursts of forced laughter. In our study Gelastic seizures were revealed in 25 patients that comprised 1,98% of all epilepsy events with onset under 18 years of age (n=1261). Male patients prevailed in the group: 16 male patients (64.0%) against 9 female patients (36.0%). Symptomatic focal epilepsy was identified most frequently - in 80% of patients. Cryptogenic focal epilepsy (probably symptomatic focal epilepsy) was defined in 20% of cases. Epilepsy onset varied in a broad age interval: from the first day after birth till 16 years, 4.53+4.52 years on average. Most often (82%) onset was observed in the first years of life - from the first days of life till 6 years old. Clinical findings may disclose 12 different types of seizures. Most frequently were observed: focal motor seizures with typical automatisms - 64% of cases, secondarily generalized tonic-clonic seizures - 48% of cases and tonic seizures - in 32% of all cases. MRI changes: hypothalamic hamartoma - 32% of cases, temporal lobe atrophy - 12% of cases, DNET - 8% of cases, focal cortical dysplasia (insular-opercular region) - 4%, local bifrontal atrophy - 8%, Tuberous Sclerosis - 8% of cases, diffuse cerebral atrophy presented in the form of ventriculomegalia was diagnosed in 2 patients - 8% of cases. Remission was achieved only in 24% of cases. Whereas, in 12% of cases seizures were blocked only after surgical intervention. Reduction of seizures frequency >50% was observed in 20% of patients. In 56% of cases AED therapy produced no significant effect.
CLINICAL CASES
30-37 1092
Abstract
Abstract: the data about seizures as the clinical manifestation of acute stroke in childhood is generalized. Authors propose the following diagnostic criteria to determine seizures as the symptom of stroke vs epilepsy debut: stable neurological signs (more than 24 hours) during the postictal period; neuroimaging data, confirming the focus of stroke; congenital heart malformations or diseases; procoagulant or hemorrhagic predisposition confirmed due to laboratory data in children or in family history; hyperhomocysteinemia; thrombophilic genes polymorphisms (more than 3) in children or in family. Clinical case of 6 y.o. boy demonstrates the time lag before seizures debut and stroke verification as the reason for those seizures.
SCIENTIFIC SURVEYS
38-44 592
Abstract
Abstract: the article provides a revised definition of epilepsy, according to the recommendations of the International League Against Epilepsy. Epilepsy can be installed after one unprovoked seizure in people who have other factors associated with a high risk of permanent lowering of the threshold of convulsive readiness. Persons with reflex seizures also attributed to epilepsy. It is resolved that epilepsy is no longer for those who had no seizures for at least 10 years without antiepileptic therapy, provided that there are no known risk factors associated with a high risk of recurrence of seizures.
ANNIVERSARY
SCIENTIFIC EVENTS
ISSN 2077-8333 (Print)
ISSN 2311-4088 (Online)
ISSN 2311-4088 (Online)