ORIGINAL ARTICLES
Abstract: an article presented the data on application of autologous multipotent mesenchymal stem cells (MMSCs) from bone marrow for therapy of 10 patients suffering from drug-resistant symptomatic epilepsy. Intravenous injection of 40.0-101.0Ч106 (mean 68.2± 8,48Ч106) MMSCs endolumbal injection of 2.7-8.0Ч106 (mean 6.34±0.72Ч106) neuroinduced MMSCs did non induced in patients unfovarable reactions an complications. Moreover, during 3-11 months of monitoring 5 of 10 patients demonstrated decrease the frequency or disappearance of seizures, severity the incidence of seizures. 2 patients demonstrated increase of cognitive functions, 2 patients – decrease the level of anxiety. We concluded that application of MMSC-base cellular therapy id safe and enable to facilitate seizure status in patients with drug-resistant symptomatic epilepsy.
Abstract: the data of analysis of probable anticonvulsive mechanisms of repetitive transcranial magnetic stimulation (rTMS) are presented on the article. The analysis bases on review of scientific publications and proper researches. Clinical, neurophysiological and neurovisualization predictors of complex therapy with rTMS course effectivity are interpreted what permit to prognoses the outcomes of new technology using and lead stimulation with reliable result of effectivity.
LITERATURE SURVEY
ISSN 2311-4088 (Online)